Does the benefit on survival from leisure time physical activity depend on physical activity at work? A Prospective Cohort Study

TY - JOUR

T1 - Does the benefit on survival from leisure time physical activity depend on physical activity at work?

T2 - A Prospective Cohort Study

AU - Holtermann, Andreas

AU - Marott, Jacob Louis

AU - Gyntelberg, Finn

AU - Søgaard, Karen

AU - Suadicani, Poul

AU - Mortensen, Ole Steen

AU - Prescott, Eva

AU - Schnohr, Peter

PY - 2013/1/17

Y1 - 2013/1/17

N2 - Purpose: To investigate if persons with high physical activity at work have the same benefits from leisure time physical activity as persons with sedentary work. Methods: In the Copenhagen City Heart Study, a prospective cohort of 7,411 males and 8,916 females aged 25-66 years without known cardiovascular disease at entry in 1976-78, 1981-83, 1991-94, or 2001-03, the authors analyzed with sex-stratified multivariate Cox proportional hazards regression the association between leisure time physical activity and cardiovascular and all-cause mortality among individuals with different levels of occupational physical activity. Results: During a median follow-up of 22.4 years, 4,003 individuals died from cardiovascular disease and 8,935 from all-causes. Irrespective of level of occupational physical activity, a consistently lower risk with increasing leisure time physical activity was found for both cardiovascular and all-cause mortality among both men and women. Compared to low leisure time physical activity, the survival benefit ranged from 1.5-3.6 years for moderate and 2.6-4.7 years for high leisure time physical activity among the different levels of occupational physical activity. Conclusion: Public campaigns and initiatives for increasing physical activity in the working population should target everybody, irrespective of physical activity at work.

AB - Purpose: To investigate if persons with high physical activity at work have the same benefits from leisure time physical activity as persons with sedentary work. Methods: In the Copenhagen City Heart Study, a prospective cohort of 7,411 males and 8,916 females aged 25-66 years without known cardiovascular disease at entry in 1976-78, 1981-83, 1991-94, or 2001-03, the authors analyzed with sex-stratified multivariate Cox proportional hazards regression the association between leisure time physical activity and cardiovascular and all-cause mortality among individuals with different levels of occupational physical activity. Results: During a median follow-up of 22.4 years, 4,003 individuals died from cardiovascular disease and 8,935 from all-causes. Irrespective of level of occupational physical activity, a consistently lower risk with increasing leisure time physical activity was found for both cardiovascular and all-cause mortality among both men and women. Compared to low leisure time physical activity, the survival benefit ranged from 1.5-3.6 years for moderate and 2.6-4.7 years for high leisure time physical activity among the different levels of occupational physical activity. Conclusion: Public campaigns and initiatives for increasing physical activity in the working population should target everybody, irrespective of physical activity at work.

U2 - 10.1371/journal.pone.0054548

DO - 10.1371/journal.pone.0054548

M3 - Journal article

C2 - 23349926

SN - 1932-6203

VL - 8

JO - PLoS Computational Biology

JF - PLoS Computational Biology

IS - 1

M1 - e54548

ER -