Does aerobic exercise increase 24-hour ambulatory blood pressure among workers with high occupational physical activity? - A RCT

TY - JOUR

T1 - Does aerobic exercise increase 24-hour ambulatory blood pressure among workers with high occupational physical activity? - A RCT

AU - Korshøj, Mette

AU - Krause, Niklas

AU - Clays, Els

AU - Søgaard, Karen

AU - Krustrup, Peter

AU - Holtermann, Andreas

N1 - CURIS 2017 NEXS 060

PY - 2017/4/1

Y1 - 2017/4/1

N2 - OBJECTIVE High occupational physical activity (OPA) increases cardiovascular risk and aerobic exercise has been recommended for reducing this risk. This paper investigates the effects of an aerobic exercise intervention on 24-hour ambulatory blood pressure (ABP) among cleaners with high OPA. METHODS Hundred and sixteen cleaners between 18 and 65 years were randomized. During the 4-month intervention period, the aerobic exercise group (AE) (n = 57) performed worksite aerobic exercise (2 × 30 minutes/week), while the reference group (REF) (n = 59) attended lectures. Between-group differences in 4-month ABP changes were evaluated by intention-to-treat analysis using a repeated-measure 2 × 2 multiadjusted mixed-models design. RESULTS Relative to REF, 24-hour ABP signifcantly increased in AE: systolic 3.6 mm Hg (95% confdence interval (CI) 1.6-5.7) and diastolic 2.3 mm Hg (95% CI 0.9-3.8). Cleaners with high aerobic workload exhibited particularly high 24-hour ABP increases: systolic 6.0 mm Hg (95% CI 2.4-9.6), and diastolic 3.8 mm Hg (95% CI 1.3-6.4). CONCLUSION Aerobic exercise increased 24-hour ABP among cleaners. This adverse effect raises questions about the safety and intended benefts of aerobic exercise, especially among workers with high OPA and a demanding aerobic workload.

AB - OBJECTIVE High occupational physical activity (OPA) increases cardiovascular risk and aerobic exercise has been recommended for reducing this risk. This paper investigates the effects of an aerobic exercise intervention on 24-hour ambulatory blood pressure (ABP) among cleaners with high OPA. METHODS Hundred and sixteen cleaners between 18 and 65 years were randomized. During the 4-month intervention period, the aerobic exercise group (AE) (n = 57) performed worksite aerobic exercise (2 × 30 minutes/week), while the reference group (REF) (n = 59) attended lectures. Between-group differences in 4-month ABP changes were evaluated by intention-to-treat analysis using a repeated-measure 2 × 2 multiadjusted mixed-models design. RESULTS Relative to REF, 24-hour ABP signifcantly increased in AE: systolic 3.6 mm Hg (95% confdence interval (CI) 1.6-5.7) and diastolic 2.3 mm Hg (95% CI 0.9-3.8). Cleaners with high aerobic workload exhibited particularly high 24-hour ABP increases: systolic 6.0 mm Hg (95% CI 2.4-9.6), and diastolic 3.8 mm Hg (95% CI 1.3-6.4). CONCLUSION Aerobic exercise increased 24-hour ABP among cleaners. This adverse effect raises questions about the safety and intended benefts of aerobic exercise, especially among workers with high OPA and a demanding aerobic workload.

KW - Blood pressure

KW - Cleaners

KW - Hypertesion

KW - Objective measurements

KW - Worksite intervention

U2 - 10.1093/ajh/hpw197

DO - 10.1093/ajh/hpw197

M3 - Journal article

C2 - 28203695

SN - 0895-7061

VL - 30

SP - 444

EP - 450

JO - American Journal of Hypertension

JF - American Journal of Hypertension

IS - 4

ER -