Dissolution properties of co-amorphous drug-amino acid formulations in buffer and biorelevant media

Keyphrases

• Amorphous Formulation 100%
• Amorphization 100%
• Amorphous Drug 100%
• Buffered Media 100%
• Dissolution Properties 100%
• Biorelevant Media 100%
• Amino Acid Complex 100%
• Glibenclamide 66%
• Crystalline Drug 66%
• Threonine 66%
• Supersaturation 66%
• Simulated Intestinal Fluid 66%
• Aqueous Buffer 33%
• Fasted State 33%
• FaSSIF 33%
• Fed State 33%
• Biorelevant 33%
• Lysine 33%
• Simvastatin 33%
• Amorphous State 33%
• Dissolution Enhancement 33%
• Dissolution Studies 33%
• Physical Stability 33%
• Phosphate Buffer 33%
• Solubility Properties 33%
• Poorly Water-soluble Drugs 33%
• Intrinsic Dissolution Rate 33%
• Oral Bioavailability 33%
• Buffer pH 33%
• Biopharmaceutics Classification System 33%

Pharmacology, Toxicology and Pharmaceutical Science

• Buffer 100%
• Amino Acid 100%
• Glibenclamide 40%
• Serine 40%
• Threonine 40%
• Lysine 20%
• Amino Acid Mixture 20%
• Pharmaceutics 20%
• Simvastatin 20%
• Bioavailability 20%