Development of composite outcomes for individual patient data (IPD) meta-analysis on the effects of diet and lifestyle in pregnancy: A Delphi survey

E. Rogozinska; M. I. D'Amico; K. S. Khan; J. G. Cecatti; H. Teede; S. Yeo; C. A. Vinter; G. Rayanagoudar; R. Barakat; M. Perales; J. M. Dodd; R. Devlieger; A. Bogaerts; M. N.M. Van Poppel; L. Haakstad; G. X. Shen; A. Shub; R. Luoto; T. I. Kinnunen; S. Phelan; L. Poston; T. T. Scudeller; N. El Beltagy; S. N. Stafne; S. Tonstad; Nina Rica Wium Geiker; A. E. Ruifrok; B. W. Mol; A. Coomarasamy; S. Thangaratinam

doi:10.1111/1471-0528.13764

Development of composite outcomes for individual patient data (IPD) meta-analysis on the effects of diet and lifestyle in pregnancy: A Delphi survey

E. Rogozinska^*, M. I. D'Amico, K. S. Khan, J. G. Cecatti, H. Teede, S. Yeo, C. A. Vinter, G. Rayanagoudar, R. Barakat, M. Perales, J. M. Dodd, R. Devlieger, A. Bogaerts, M. N.M. Van Poppel, L. Haakstad, G. X. Shen, A. Shub, R. Luoto, T. I. Kinnunen, S. PhelanL. Poston, T. T. Scudeller, N. El Beltagy, S. N. Stafne, S. Tonstad, Nina Rica Wium Geiker, A. E. Ruifrok, B. W. Mol, A. Coomarasamy, S. Thangaratinam

^*Corresponding author for this work

Department of Clinical Medicine

19 Citations (Scopus)

Abstract

Objective: To develop maternal, fetal, and neonatal composite outcomes relevant to the evaluation of diet and lifestyle interventions in pregnancy by individual patient data (IPD) meta-analysis.

Design: Delphi survey.

Setting: The International Weight Management in Pregnancy (i-WIP) collaborative network. Sample Twenty-six researchers from the i-WIP collaborative network from 11 countries.

Methods: A two-generational Delphi survey involving members of the i-WIP collaborative network (26 members in 11 countries) was undertaken to prioritise the individual outcomes for their importance in clinical care. The final components of the composite outcomes were identified using pre-specified criteria.

Main outcome measures: Composite outcomes considered to be important for the evaluation of the effect of diet and lifestyle in pregnancy. Results Of the 36 maternal outcomes, nine were prioritised and the following were included in the final composite: pre-eclampsia or pregnancy-induced hypertension, gestational diabetes mellitus (GDM), elective or emergency caesarean section, and preterm delivery. Of the 27 fetal and neonatal outcomes, nine were further evaluated, with the final composite consisting of intrauterine death, small for gestational age, large for gestational age, and admission to a neonatal intensive care unit (NICU).

Conclusions: Our work has identified the components of maternal, fetal, and neonatal composite outcomes required for the assessment of diet and lifestyle interventions in pregnancy by IPD meta-analysis.

Tweetable abstract: Composite outcomes in IPD meta-analysis on diet and lifestyle in pregnancy.

This article includes Author Insights, a video abstract available at https://vimeo.com/148890226

Original language	English
Journal	BJOG: An International Journal of Obstetrics and Gynaecology
Volume	123
Issue number	2
Pages (from-to)	190-198
Number of pages	9
ISSN	1470-0328
DOIs	https://doi.org/10.1111/1471-0528.13764
Publication status	Published - 2016

Keywords

Composite outcome
Delphi survey
Diet
Fetal
Lifestyle
Maternal
Neonatal

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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Rogozinska, E., D'Amico, M. I., Khan, K. S., Cecatti, J. G., Teede, H., Yeo, S., Vinter, C. A., Rayanagoudar, G., Barakat, R., Perales, M., Dodd, J. M., Devlieger, R., Bogaerts, A., Van Poppel, M. N. M., Haakstad, L., Shen, G. X., Shub, A., Luoto, R., Kinnunen, T. I., ... Thangaratinam, S. (2016). Development of composite outcomes for individual patient data (IPD) meta-analysis on the effects of diet and lifestyle in pregnancy: A Delphi survey. BJOG: An International Journal of Obstetrics and Gynaecology, 123(2), 190-198. https://doi.org/10.1111/1471-0528.13764

Development of composite outcomes for individual patient data (IPD) meta-analysis on the effects of diet and lifestyle in pregnancy: A Delphi survey. / Rogozinska, E.; D'Amico, M. I.; Khan, K. S. et al.
In: BJOG: An International Journal of Obstetrics and Gynaecology, Vol. 123, No. 2, 2016, p. 190-198.

Research output: Contribution to journal › Journal article › Research › peer-review

Rogozinska, E, D'Amico, MI, Khan, KS, Cecatti, JG, Teede, H, Yeo, S, Vinter, CA, Rayanagoudar, G, Barakat, R, Perales, M, Dodd, JM, Devlieger, R, Bogaerts, A, Van Poppel, MNM, Haakstad, L, Shen, GX, Shub, A, Luoto, R, Kinnunen, TI, Phelan, S, Poston, L, Scudeller, TT, El Beltagy, N, Stafne, SN, Tonstad, S, Geiker, NRW, Ruifrok, AE, Mol, BW, Coomarasamy, A & Thangaratinam, S 2016, 'Development of composite outcomes for individual patient data (IPD) meta-analysis on the effects of diet and lifestyle in pregnancy: A Delphi survey', BJOG: An International Journal of Obstetrics and Gynaecology, vol. 123, no. 2, pp. 190-198. https://doi.org/10.1111/1471-0528.13764

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abstract = "Objective: To develop maternal, fetal, and neonatal composite outcomes relevant to the evaluation of diet and lifestyle interventions in pregnancy by individual patient data (IPD) meta-analysis. Design: Delphi survey. Setting: The International Weight Management in Pregnancy (i-WIP) collaborative network. Sample Twenty-six researchers from the i-WIP collaborative network from 11 countries. Methods: A two-generational Delphi survey involving members of the i-WIP collaborative network (26 members in 11 countries) was undertaken to prioritise the individual outcomes for their importance in clinical care. The final components of the composite outcomes were identified using pre-specified criteria. Main outcome measures: Composite outcomes considered to be important for the evaluation of the effect of diet and lifestyle in pregnancy. Results Of the 36 maternal outcomes, nine were prioritised and the following were included in the final composite: pre-eclampsia or pregnancy-induced hypertension, gestational diabetes mellitus (GDM), elective or emergency caesarean section, and preterm delivery. Of the 27 fetal and neonatal outcomes, nine were further evaluated, with the final composite consisting of intrauterine death, small for gestational age, large for gestational age, and admission to a neonatal intensive care unit (NICU). Conclusions: Our work has identified the components of maternal, fetal, and neonatal composite outcomes required for the assessment of diet and lifestyle interventions in pregnancy by IPD meta-analysis. Tweetable abstract: Composite outcomes in IPD meta-analysis on diet and lifestyle in pregnancy. This article includes Author Insights, a video abstract available at https://vimeo.com/148890226",

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author = "E. Rogozinska and D'Amico, {M. I.} and Khan, {K. S.} and Cecatti, {J. G.} and H. Teede and S. Yeo and Vinter, {C. A.} and G. Rayanagoudar and R. Barakat and M. Perales and Dodd, {J. M.} and R. Devlieger and A. Bogaerts and {Van Poppel}, {M. N.M.} and L. Haakstad and Shen, {G. X.} and A. Shub and R. Luoto and Kinnunen, {T. I.} and S. Phelan and L. Poston and Scudeller, {T. T.} and {El Beltagy}, N. and Stafne, {S. N.} and S. Tonstad and Geiker, {Nina Rica Wium} and Ruifrok, {A. E.} and Mol, {B. W.} and A. Coomarasamy and S. Thangaratinam",

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doi = "10.1111/1471-0528.13764",

language = "English",

volume = "123",

pages = "190--198",

journal = "BJOG: An International Journal of Obstetrics and Gynaecology",

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T1 - Development of composite outcomes for individual patient data (IPD) meta-analysis on the effects of diet and lifestyle in pregnancy

T2 - A Delphi survey

AU - Rogozinska, E.

AU - D'Amico, M. I.

AU - Khan, K. S.

AU - Cecatti, J. G.

AU - Teede, H.

AU - Yeo, S.

AU - Vinter, C. A.

AU - Rayanagoudar, G.

AU - Barakat, R.

AU - Perales, M.

AU - Dodd, J. M.

AU - Devlieger, R.

AU - Bogaerts, A.

AU - Van Poppel, M. N.M.

AU - Haakstad, L.

AU - Shen, G. X.

AU - Shub, A.

AU - Luoto, R.

AU - Kinnunen, T. I.

AU - Phelan, S.

AU - Poston, L.

AU - Scudeller, T. T.

AU - El Beltagy, N.

AU - Stafne, S. N.

AU - Tonstad, S.

AU - Geiker, Nina Rica Wium

AU - Ruifrok, A. E.

AU - Mol, B. W.

AU - Coomarasamy, A.

AU - Thangaratinam, S.

PY - 2016

Y1 - 2016

N2 - Objective: To develop maternal, fetal, and neonatal composite outcomes relevant to the evaluation of diet and lifestyle interventions in pregnancy by individual patient data (IPD) meta-analysis. Design: Delphi survey. Setting: The International Weight Management in Pregnancy (i-WIP) collaborative network. Sample Twenty-six researchers from the i-WIP collaborative network from 11 countries. Methods: A two-generational Delphi survey involving members of the i-WIP collaborative network (26 members in 11 countries) was undertaken to prioritise the individual outcomes for their importance in clinical care. The final components of the composite outcomes were identified using pre-specified criteria. Main outcome measures: Composite outcomes considered to be important for the evaluation of the effect of diet and lifestyle in pregnancy. Results Of the 36 maternal outcomes, nine were prioritised and the following were included in the final composite: pre-eclampsia or pregnancy-induced hypertension, gestational diabetes mellitus (GDM), elective or emergency caesarean section, and preterm delivery. Of the 27 fetal and neonatal outcomes, nine were further evaluated, with the final composite consisting of intrauterine death, small for gestational age, large for gestational age, and admission to a neonatal intensive care unit (NICU). Conclusions: Our work has identified the components of maternal, fetal, and neonatal composite outcomes required for the assessment of diet and lifestyle interventions in pregnancy by IPD meta-analysis. Tweetable abstract: Composite outcomes in IPD meta-analysis on diet and lifestyle in pregnancy. This article includes Author Insights, a video abstract available at https://vimeo.com/148890226

AB - Objective: To develop maternal, fetal, and neonatal composite outcomes relevant to the evaluation of diet and lifestyle interventions in pregnancy by individual patient data (IPD) meta-analysis. Design: Delphi survey. Setting: The International Weight Management in Pregnancy (i-WIP) collaborative network. Sample Twenty-six researchers from the i-WIP collaborative network from 11 countries. Methods: A two-generational Delphi survey involving members of the i-WIP collaborative network (26 members in 11 countries) was undertaken to prioritise the individual outcomes for their importance in clinical care. The final components of the composite outcomes were identified using pre-specified criteria. Main outcome measures: Composite outcomes considered to be important for the evaluation of the effect of diet and lifestyle in pregnancy. Results Of the 36 maternal outcomes, nine were prioritised and the following were included in the final composite: pre-eclampsia or pregnancy-induced hypertension, gestational diabetes mellitus (GDM), elective or emergency caesarean section, and preterm delivery. Of the 27 fetal and neonatal outcomes, nine were further evaluated, with the final composite consisting of intrauterine death, small for gestational age, large for gestational age, and admission to a neonatal intensive care unit (NICU). Conclusions: Our work has identified the components of maternal, fetal, and neonatal composite outcomes required for the assessment of diet and lifestyle interventions in pregnancy by IPD meta-analysis. Tweetable abstract: Composite outcomes in IPD meta-analysis on diet and lifestyle in pregnancy. This article includes Author Insights, a video abstract available at https://vimeo.com/148890226

KW - Composite outcome

KW - Delphi survey

KW - Diet

KW - Fetal

KW - Lifestyle

KW - Maternal

KW - Neonatal

U2 - 10.1111/1471-0528.13764

DO - 10.1111/1471-0528.13764

M3 - Journal article

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SN - 1470-0328

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JO - BJOG: An International Journal of Obstetrics and Gynaecology

JF - BJOG: An International Journal of Obstetrics and Gynaecology

IS - 2

ER -

Development of composite outcomes for individual patient data (IPD) meta-analysis on the effects of diet and lifestyle in pregnancy: A Delphi survey

Abstract

Keywords

UN SDGs

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