Der er evidens for profylaktisk magnesiumsulfat som neuroprotektion ved præmature fødsler

Hanne Trap Wolf; Hanne Kristine Hegaard; Lene Huusom; Gorm Greisen; Morten Hedegaard

Der er evidens for profylaktisk magnesiumsulfat som neuroprotektion ved præmature fødsler

Translated title of the contribution: [Evidence exists for prophylactic magnesium sulphate as a neuroprotector in premature births]

Hanne Trap Wolf, Hanne Kristine Hegaard, Lene Huusom, Gorm Greisen, Morten Hedegaard

Abstract

Preterm birth increases the child's risk of cerebral palsy. Observational studies as well as randomized studies find that magnesium sulphate given to women in preterm birth decreases such risk. A Cochrane meta-analysis of the randomized studies shows no change in mortality, whereas some observational studies find a mortality decrease. It is important to identify the neuroprotective mechanism and to decide whether these results are relevant in the current Danish obstetrical practice. Should we use magnesium sulphate now or should questions about doses, time of administration and maternal side effects be answered first?

Translated title of the contribution	[Evidence exists for prophylactic magnesium sulphate as a neuroprotector in premature births]
Original language	Danish
Journal	Ugeskrift for Laeger
Volume	173
Issue number	13
Pages (from-to)	962-5
Number of pages	4
ISSN	0041-5782
Publication status	Published - 28 Mar 2011

Cite this

@article{5eac1001f3654ed8ba6d2f4b8a2c1f1c,

title = "Der er evidens for profylaktisk magnesiumsulfat som neuroprotektion ved pr{\ae}mature f{\o}dsler",

abstract = "Preterm birth increases the child's risk of cerebral palsy. Observational studies as well as randomized studies find that magnesium sulphate given to women in preterm birth decreases such risk. A Cochrane meta-analysis of the randomized studies shows no change in mortality, whereas some observational studies find a mortality decrease. It is important to identify the neuroprotective mechanism and to decide whether these results are relevant in the current Danish obstetrical practice. Should we use magnesium sulphate now or should questions about doses, time of administration and maternal side effects be answered first?",

author = "Wolf, {Hanne Trap} and Hegaard, {Hanne Kristine} and Lene Huusom and Gorm Greisen and Morten Hedegaard",

year = "2011",

month = mar,

day = "28",

language = "Dansk",

volume = "173",

pages = "962--5",

journal = "Ugeskrift for Laeger",

issn = "0041-5782",

publisher = "Almindelige Danske Laegeforening",

number = "13",

}

TY - JOUR

T1 - Der er evidens for profylaktisk magnesiumsulfat som neuroprotektion ved præmature fødsler

AU - Wolf, Hanne Trap

AU - Hegaard, Hanne Kristine

AU - Huusom, Lene

AU - Greisen, Gorm

AU - Hedegaard, Morten

PY - 2011/3/28

Y1 - 2011/3/28

N2 - Preterm birth increases the child's risk of cerebral palsy. Observational studies as well as randomized studies find that magnesium sulphate given to women in preterm birth decreases such risk. A Cochrane meta-analysis of the randomized studies shows no change in mortality, whereas some observational studies find a mortality decrease. It is important to identify the neuroprotective mechanism and to decide whether these results are relevant in the current Danish obstetrical practice. Should we use magnesium sulphate now or should questions about doses, time of administration and maternal side effects be answered first?

AB - Preterm birth increases the child's risk of cerebral palsy. Observational studies as well as randomized studies find that magnesium sulphate given to women in preterm birth decreases such risk. A Cochrane meta-analysis of the randomized studies shows no change in mortality, whereas some observational studies find a mortality decrease. It is important to identify the neuroprotective mechanism and to decide whether these results are relevant in the current Danish obstetrical practice. Should we use magnesium sulphate now or should questions about doses, time of administration and maternal side effects be answered first?

M3 - Tidsskriftartikel

SN - 0041-5782

VL - 173

SP - 962

EP - 965

JO - Ugeskrift for Laeger

JF - Ugeskrift for Laeger

IS - 13

ER -

Der er evidens for profylaktisk magnesiumsulfat som neuroprotektion ved præmature fødsler

Abstract

Fingerprint

Cite this