TY - JOUR
T1 - Defining antimicrobial resistance in cystic fibrosis
AU - Kidd, Timothy J
AU - Canton, Rafael
AU - Ekkelenkamp, Miquel
AU - Johansen, Helle Krogh
AU - Gilligan, Peter
AU - LiPuma, John J
AU - Bell, Scott C
AU - Elborn, J Stuart
AU - Flume, Patrick A
AU - VanDevanter, Donald R
AU - Waters, Valerie J
AU - Antimicrobial Resistance in Cystic Fibrosis International Working Group
PY - 2018/11
Y1 - 2018/11
N2 - Antimicrobial resistance (AMR) can present significant challenges in the treatment of cystic fibrosis (CF) lung infections. In CF and other chronic diseases, AMR has a different profile and clinical consequences compared to acute infections and this requires different diagnostic and treatment approaches. This review defines AMR, explains how it occurs, describes the methods used to measure AMR as well as their limitations, and concludes with future directions for research and development in the area of AMR in CF.
AB - Antimicrobial resistance (AMR) can present significant challenges in the treatment of cystic fibrosis (CF) lung infections. In CF and other chronic diseases, AMR has a different profile and clinical consequences compared to acute infections and this requires different diagnostic and treatment approaches. This review defines AMR, explains how it occurs, describes the methods used to measure AMR as well as their limitations, and concludes with future directions for research and development in the area of AMR in CF.
U2 - 10.1016/j.jcf.2018.08.014
DO - 10.1016/j.jcf.2018.08.014
M3 - Review
C2 - 30266518
SN - 1569-1993
VL - 17
SP - 696
EP - 704
JO - Journal of Cystic Fibrosis
JF - Journal of Cystic Fibrosis
IS - 6
ER -