Abstract
Zur hypothetischen “RNA-Welt” gibt es eine realistische Alternative, indem Peptide von stochastischen Sequenzen in ein autokatalytisches System von Quasiproteinen gelangten. Einige dieser Komponenten synthetisierten metabolische Coenzyme, unter denen geeignete Ribonukleotide zur Effektivisierung der Proteinsynthese herangezogen wurden. Hieraus gingen dann Ribosomen und andere RNA-Moleküle hervor. Die thermodynamischen Voraussetzungen wurden am besten im Gezeitenwechsel der Meeresküste gewährleistet.
A reasonable alternative to the 'RNA first' conception of a hypothetical RNA world is based on two generations of preexisting peptides – from stochastic sequences to an autocatalytic system of quasi-proteins. Some of these catalysts provided a variety of metabolic coenzymes, among which a suitable set of ribonucleotides engaged in a more efficient mode of protein synthesis. Such components evolved into ribosomes and other kinds of RNA. The thermodynamic requirements were best met in the tidal zone near major estuaries.
A reasonable alternative to the 'RNA first' conception of a hypothetical RNA world is based on two generations of preexisting peptides – from stochastic sequences to an autocatalytic system of quasi-proteins. Some of these catalysts provided a variety of metabolic coenzymes, among which a suitable set of ribonucleotides engaged in a more efficient mode of protein synthesis. Such components evolved into ribosomes and other kinds of RNA. The thermodynamic requirements were best met in the tidal zone near major estuaries.
Original language | German |
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Journal | Biologie in Unserer Zeit |
Volume | 40 |
Issue number | 1 |
Pages (from-to) | 36-44 |
ISSN | 0045-205X |
DOIs | |
Publication status | Published - 2010 |
Keywords
- Faculty of Science