Abstract
Chronic urticaria is an itchy skin disease, which is treated with antihistamines; however, a large group of patients are unresponsive to antihistamines alone and are thus treated with omalizumab, although a small fraction of these patients have particularly recalcitrant disease. Currently, there are no reliable biomarkers available to assess disease activity/severity and treatment response in chronic urticaria patients. However, it has been reported that high levels of d-dimer are observed during disease activity and are significantly reduced during periods of remission. We present a focused overview of studies investigating plasma d-dimer level as a biomarker for disease activity and treatment response in patients with chronic urticaria.
| Original language | English |
|---|---|
| Journal | European Journal of Dermatology |
| Volume | 28 |
| Issue number | 6 |
| Pages (from-to) | 731-735 |
| ISSN | 1167-1122 |
| DOIs | |
| Publication status | Published - 1 Nov 2018 |
Keywords
- chronic urticaria
- D-dimer
- biomarker
- disease activity
- treatment response