Dødelighed--selvmord og naturlig død--blandt deprimerede patienter. Relationen til depressionstype

P E Hansen; A G Wang; P Kragh-Sørensen

Dødelighed--selvmord og naturlig død--blandt deprimerede patienter. Relationen til depressionstype

Translated title of the contribution: Mortality--suicide and natural death--among depressed patients. Relation to type of depression

P E Hansen, A G Wang, P Kragh-Sørensen

Abstract

A total of 219 inpatients with a DSM-III diagnosis of major depression, (150 women and 69 men), were followed prospectively for three to ten years and mortality was recorded. The patients were previous participants in psychopharmacological multicentre trials, which were carried out for the purpose of comparing the antidepressant effect of newer selective serotonin reuptake inhibitors (SSRI), citalopram and paroxetine, with that of the tricyclic antidepressant drug, clomipramine. Diagnostic classification according to the Newcastle-I Scale into endogenous and nonendogenous depression was performed. The observed mortality was significantly greater than that expected. The increased mortality was essentially due to suicides and mainly found among women. Patients scored as being nonendogenously depressed had a significantly higher suicide rate than endogenously depressed patients. The excess number of suicides in the nonendogenous group largely occurred within the first year of observation. No association was found between response to the antidepressant treatment in the trial and the suicide risk during the first three years of observation.
Udgivelsesdato: 1994-Nov-28

Translated title of the contribution	Mortality--suicide and natural death--among depressed patients. Relation to type of depression
Original language	Danish
Journal	Ugeskrift for Laeger
Volume	156
Issue number	48
Pages (from-to)	7224-8
Number of pages	4
ISSN	0041-5782
Publication status	Published - 1994

Cite this

@article{e48dbb9288bf4d99b295b9b3cfc6ce2a,

title = "D{\o}delighed--selvmord og naturlig d{\o}d--blandt deprimerede patienter. Relationen til depressionstype",

abstract = "A total of 219 inpatients with a DSM-III diagnosis of major depression, (150 women and 69 men), were followed prospectively for three to ten years and mortality was recorded. The patients were previous participants in psychopharmacological multicentre trials, which were carried out for the purpose of comparing the antidepressant effect of newer selective serotonin reuptake inhibitors (SSRI), citalopram and paroxetine, with that of the tricyclic antidepressant drug, clomipramine. Diagnostic classification according to the Newcastle-I Scale into endogenous and nonendogenous depression was performed. The observed mortality was significantly greater than that expected. The increased mortality was essentially due to suicides and mainly found among women. Patients scored as being nonendogenously depressed had a significantly higher suicide rate than endogenously depressed patients. The excess number of suicides in the nonendogenous group largely occurred within the first year of observation. No association was found between response to the antidepressant treatment in the trial and the suicide risk during the first three years of observation. Udgivelsesdato: 1994-Nov-28",

author = "Hansen, {P E} and Wang, {A G} and P Kragh-S{\o}rensen",

note = "Keywords: Adult; Aged; Cause of Death; Denmark; Depression; Depressive Disorder; Female; Follow-Up Studies; Humans; Male; Middle Aged; Prospective Studies; Suicide",

year = "1994",

language = "Dansk",

volume = "156",

pages = "7224--8",

journal = "Ugeskrift for Laeger",

issn = "0041-5782",

publisher = "Almindelige Danske Laegeforening",

number = "48",

}

TY - JOUR

T1 - Dødelighed--selvmord og naturlig død--blandt deprimerede patienter. Relationen til depressionstype

AU - Hansen, P E

AU - Wang, A G

AU - Kragh-Sørensen, P

N1 - Keywords: Adult; Aged; Cause of Death; Denmark; Depression; Depressive Disorder; Female; Follow-Up Studies; Humans; Male; Middle Aged; Prospective Studies; Suicide

PY - 1994

Y1 - 1994

N2 - A total of 219 inpatients with a DSM-III diagnosis of major depression, (150 women and 69 men), were followed prospectively for three to ten years and mortality was recorded. The patients were previous participants in psychopharmacological multicentre trials, which were carried out for the purpose of comparing the antidepressant effect of newer selective serotonin reuptake inhibitors (SSRI), citalopram and paroxetine, with that of the tricyclic antidepressant drug, clomipramine. Diagnostic classification according to the Newcastle-I Scale into endogenous and nonendogenous depression was performed. The observed mortality was significantly greater than that expected. The increased mortality was essentially due to suicides and mainly found among women. Patients scored as being nonendogenously depressed had a significantly higher suicide rate than endogenously depressed patients. The excess number of suicides in the nonendogenous group largely occurred within the first year of observation. No association was found between response to the antidepressant treatment in the trial and the suicide risk during the first three years of observation. Udgivelsesdato: 1994-Nov-28

AB - A total of 219 inpatients with a DSM-III diagnosis of major depression, (150 women and 69 men), were followed prospectively for three to ten years and mortality was recorded. The patients were previous participants in psychopharmacological multicentre trials, which were carried out for the purpose of comparing the antidepressant effect of newer selective serotonin reuptake inhibitors (SSRI), citalopram and paroxetine, with that of the tricyclic antidepressant drug, clomipramine. Diagnostic classification according to the Newcastle-I Scale into endogenous and nonendogenous depression was performed. The observed mortality was significantly greater than that expected. The increased mortality was essentially due to suicides and mainly found among women. Patients scored as being nonendogenously depressed had a significantly higher suicide rate than endogenously depressed patients. The excess number of suicides in the nonendogenous group largely occurred within the first year of observation. No association was found between response to the antidepressant treatment in the trial and the suicide risk during the first three years of observation. Udgivelsesdato: 1994-Nov-28

M3 - Tidsskriftartikel

SN - 0041-5782

VL - 156

SP - 7224

EP - 7228

JO - Ugeskrift for Laeger

JF - Ugeskrift for Laeger

IS - 48

ER -