Current and Emerging Treatment Options in Diabetes Care

Christoffer Clemmensen, Timo D Müller, Brian Finan, Matthias H Tschöp, Richard DiMarchi

15 Citations (Scopus)

Abstract

Diabetes constitutes an increasing threat to human health, particularly in newly industrialized and densely populated countries. Type 1 and type 2 diabetes arise from different etiologies but lead to similar metabolic derangements constituted by an absolute or relative lack of insulin that results in elevated plasma glucose. In the last three decades, a set of new medicines built upon a deeper understanding of physiology and diabetic pathology have emerged to enhance the clinical management of the disease and related disorders. Recent insights into insulin-dependent and insulin-independent molecular events have accelerated the generation of a series of novel medicinal agents, which hold the promise for further advances in the management of diabetes. In this chapter, we provide a historical context for what has been accomplished to provide perspective for future research and novel emerging treatment options.

Original languageEnglish
Title of host publicationMetabolic Control
Number of pages23
Volume233
PublisherSpringer
Publication date2015
Pages437-459
ISBN (Print)978-3-319-29804-7
ISBN (Electronic)978-3-319-29806-1
DOIs
Publication statusPublished - 2015
Externally publishedYes
SeriesHandbook of Experimental Pharmacology
Number233
ISSN0171-2004

Keywords

  • Anti-Obesity Agents
  • Bariatric Surgery
  • Diabetes Mellitus
  • Fibroblast Growth Factors
  • Glucose
  • Humans
  • Hypoglycemic Agents
  • Leptin
  • Pancreas Transplantation
  • Journal Article
  • Review

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