Cost-effectiveness of human papillomavirus vaccine in reducing the risk of cervical cancer in Ireland due to HPV types 16 and 18 using a transmission dynamic model

Translated title of the contribution: Cost-effectiveness of human papillomavirus vaccine in reducing the risk of cervical cancer in Ireland due to HPV types 16 and 18 using a transmission dynamic model

C. Usher, L. Tilson, J. Olsen, M. Jepsen, C. Walsh, M. Barry, Martin Rudbeck Jepsen

36 Citations (Scopus)

Abstract

We evaluated the cost-effectiveness of combining a cervical cancer screening programme with a national HPV vaccination programme compared to a screening programme alone to prevent cervical dysplasia and cervical cancer related to HPV types 16 and 18 in the Irish healthcare setting. The incremental cost effectiveness of vaccination strategies for 12-year-old females (base-case) and 12-26-year-old catch-up vaccination strategies were examined. The base-case incremental cost-effectiveness ratio was (sic)17,383/LYG. Using a probabilistic sensitivity analysis about the base-case, the 95% CI for cost per LYG was ((sic)3400 to E38,400). This suggests that vaccination against HPV types 16 and 18 would be cost-effective from the perspective of the Irish healthcare payer. (C) 2008 Elsevier Ltd. All rights reserved
Translated title of the contributionCost-effectiveness of human papillomavirus vaccine in reducing the risk of cervical cancer in Ireland due to HPV types 16 and 18 using a transmission dynamic model
Original languageUndefined/Unknown
JournalVaccine
Volume26
Issue number44
Pages (from-to)5654-5661
Number of pages8
ISSN0264-410X
Publication statusPublished - 2008

Keywords

  • DYNAMIC-MODEL
  • MODEL
  • PERSPECTIVE
  • STRATEGIES

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