Corticotropin-releasing factor (CRF) in stress and disease: A review of literature and treatment perspectives with special emphasis on psychiatric disorders

K. Krohg, I. Hageman, M.B. Jorgensen

14 Citations (Scopus)

Abstract

The CRF family of neuropeptides and receptors is involved in a variety of stress responses, in the regulation of appetite, metabolic and inflammatory processes as well as intestinal movements. From a primarily psychiatric perspective, the present paper reviews the literature on its anatomy, physiology and its involvement in psychiatric, neurological and inflammatory diseases. Finally, recent developments in the pharmacological aspects of CRF in these diseases are reviewed
Udgivelsesdato: 2008
Original languageEnglish
JournalNordic Journal of Psychiatry
Volume62
Issue number1
Pages (from-to)8-16
Number of pages8
ISSN0803-9488
Publication statusPublished - 2008

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