Corneal Myofibroma (Keloid) in a Young Patient with Neurofibromatosis Type 2

Lisa Zimmermann; Thomas Reinhard; Clemens Lange; Steffen Heegaard; Claudia Auw-Haedrich

doi:10.1159/000457959

Corneal Myofibroma (Keloid) in a Young Patient with Neurofibromatosis Type 2

Lisa Zimmermann, Thomas Reinhard, Clemens Lange, Steffen Heegaard, Claudia Auw-Haedrich

Department of Clinical Medicine

2 Citations (Scopus)

Abstract

We present a 27-year-old male patient with neurofibromatosis type 2 (NF2), facial palsy, and lagophthalmos following acoustic neuroma removal and an impressing vascularized corneal tumor, which was excised. Histology showed a fibrous tumor with small vessels, and immunohistochemistry was positive for vimentin and negative for smooth muscle actin, S100, and GFAP. We assume a corneal myofibroma (keloid), which in this case rather represents a reactive lesion. This entity has not been described before in NF2 or in facial palsy-associated lagophthalmos in general.

Original language	English
Journal	Ocular Oncology and Pathology
Volume	3
Issue number	4
Pages (from-to)	247-249
Number of pages	3
ISSN	2296-4681
DOIs	https://doi.org/10.1159/000457959
Publication status	Published - 1 Nov 2017

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title = "Corneal Myofibroma (Keloid) in a Young Patient with Neurofibromatosis Type 2",

abstract = "We present a 27-year-old male patient with neurofibromatosis type 2 (NF2), facial palsy, and lagophthalmos following acoustic neuroma removal and an impressing vascularized corneal tumor, which was excised. Histology showed a fibrous tumor with small vessels, and immunohistochemistry was positive for vimentin and negative for smooth muscle actin, S100, and GFAP. We assume a corneal myofibroma (keloid), which in this case rather represents a reactive lesion. This entity has not been described before in NF2 or in facial palsy-associated lagophthalmos in general.",

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T1 - Corneal Myofibroma (Keloid) in a Young Patient with Neurofibromatosis Type 2

AU - Zimmermann, Lisa

AU - Reinhard, Thomas

AU - Lange, Clemens

AU - Heegaard, Steffen

AU - Auw-Haedrich, Claudia

PY - 2017/11/1

Y1 - 2017/11/1

N2 - We present a 27-year-old male patient with neurofibromatosis type 2 (NF2), facial palsy, and lagophthalmos following acoustic neuroma removal and an impressing vascularized corneal tumor, which was excised. Histology showed a fibrous tumor with small vessels, and immunohistochemistry was positive for vimentin and negative for smooth muscle actin, S100, and GFAP. We assume a corneal myofibroma (keloid), which in this case rather represents a reactive lesion. This entity has not been described before in NF2 or in facial palsy-associated lagophthalmos in general.

AB - We present a 27-year-old male patient with neurofibromatosis type 2 (NF2), facial palsy, and lagophthalmos following acoustic neuroma removal and an impressing vascularized corneal tumor, which was excised. Histology showed a fibrous tumor with small vessels, and immunohistochemistry was positive for vimentin and negative for smooth muscle actin, S100, and GFAP. We assume a corneal myofibroma (keloid), which in this case rather represents a reactive lesion. This entity has not been described before in NF2 or in facial palsy-associated lagophthalmos in general.

U2 - 10.1159/000457959

DO - 10.1159/000457959

M3 - Journal article

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ER -

Corneal Myofibroma (Keloid) in a Young Patient with Neurofibromatosis Type 2

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