Copenhagen pancreatitis study: An interim report from a prospective epidemiological multicentre study

Jens Rikardt Andersen; The Copenhagen Pancreatitis Study Group

doi:10.3109/00365528109181973

Copenhagen pancreatitis study: An interim report from a prospective epidemiological multicentre study

Jens Rikardt Andersen, The Copenhagen Pancreatitis Study Group

98 Citations (Scopus)

Abstract

During the past 2 decades an increasing number of patients with pancreatitis have been admitted to the Copenhagen hospitals. For this reason all departments receiving such patients from the city of Copenhagen initiated the Copenhagen Pancreatitis Study (CPS), to provide a prospective recording of all pancreatitis patients from this geographical area and to conduct yearly follow-up studies of the patients. The aims of the CPS were, first, to establish data on the incidence, prevalence, and clinical characteristics of pancreatitis, and, second, to evaluate the accuracy of diagnostic tests applied and to provide data on the natural history and the prognosis under current therapy. The present study is an interim report on 343 patients from the initial 1 1/2 years of the CPS. Pancreatitis patients are listed in four diagnostic groups: I. Possible acute pancreatitis; II. Acute pancreatitis; III. Possible chronic pancreatitis; IV. Chronic pancreatitis. The incidence rates per year per 100,000 citizens aged 20 years or more (population aged 20 years or more: 417,000) were as follows: total, 36.3; I, 6.2; II, 21.9; III, 4.2; IV, 4.0. The prevalence for the chronic types on 31 August 1979 per 100,000 citizens aged 20 years or more was as follows: total, 27.4; III, 14.4; IV, 13.0. Gallstones were found in 1/3 of the acute and 1/10 of the chronic cases. Alcohol consumption was more than 50g/day in nearly half of the patients. Acute pancreatitis was dominated by a high leukocyte count, hyperbilirubinaemia, raised aminotransferases and blood glucose levels, and low albumin and calcium levels in serum. In chronic pancreatitis 1/3 had steatorrhoea; 1/6 regularly used morphine, and 1/4 had impaired liver function. It is concluded that the incidence rates of acute and chronic pancreatitis in Copenhagen seem to be higher than those reported elsewhere; however, differences in diagnostic criteria may play a role. The clinical and laboratory findings are in agreement with other studies.

Original language	English
Book series	Scandinavian Journal of Gastroenterology
Volume	16
Issue number	2
Pages (from-to)	305-312
Number of pages	8
ISSN	0036-5521
DOIs	https://doi.org/10.3109/00365528109181973
Publication status	Published - 1981

Keywords

Abdomen, acute condition
Alcohol drinking
Amylase
Blood sugar
Calcium
Cholelithiasis
Epidemiology
Liver disease
Morphine
Pancreatic disease
Pancreatitis
Prospective studies

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10.3109/00365528109181973

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title = "Copenhagen pancreatitis study: An interim report from a prospective epidemiological multicentre study",

abstract = "During the past 2 decades an increasing number of patients with pancreatitis have been admitted to the Copenhagen hospitals. For this reason all departments receiving such patients from the city of Copenhagen initiated the Copenhagen Pancreatitis Study (CPS), to provide a prospective recording of all pancreatitis patients from this geographical area and to conduct yearly follow-up studies of the patients. The aims of the CPS were, first, to establish data on the incidence, prevalence, and clinical characteristics of pancreatitis, and, second, to evaluate the accuracy of diagnostic tests applied and to provide data on the natural history and the prognosis under current therapy. The present study is an interim report on 343 patients from the initial 1 1/2 years of the CPS. Pancreatitis patients are listed in four diagnostic groups: I. Possible acute pancreatitis; II. Acute pancreatitis; III. Possible chronic pancreatitis; IV. Chronic pancreatitis. The incidence rates per year per 100,000 citizens aged 20 years or more (population aged 20 years or more: 417,000) were as follows: total, 36.3; I, 6.2; II, 21.9; III, 4.2; IV, 4.0. The prevalence for the chronic types on 31 August 1979 per 100,000 citizens aged 20 years or more was as follows: total, 27.4; III, 14.4; IV, 13.0. Gallstones were found in 1/3 of the acute and 1/10 of the chronic cases. Alcohol consumption was more than 50g/day in nearly half of the patients. Acute pancreatitis was dominated by a high leukocyte count, hyperbilirubinaemia, raised aminotransferases and blood glucose levels, and low albumin and calcium levels in serum. In chronic pancreatitis 1/3 had steatorrhoea; 1/6 regularly used morphine, and 1/4 had impaired liver function. It is concluded that the incidence rates of acute and chronic pancreatitis in Copenhagen seem to be higher than those reported elsewhere; however, differences in diagnostic criteria may play a role. The clinical and laboratory findings are in agreement with other studies.",

keywords = "Abdomen, acute condition, Alcohol drinking, Amylase, Blood sugar, Calcium, Cholelithiasis, Epidemiology, Liver disease, Morphine, Pancreatic disease, Pancreatitis, Prospective studies",

author = "Andersen, {Jens Rikardt} and O Backer and Balsl{\o}v, {J T} and O. Bonnevie and F Burcharth and I Christoffersen and P Christoffersen and B Clausen and D Ehlers and K Fischermann and Frederiksen, {H J} and R Friedberg and B Hamilton and F Hardt and J Hegnh{\o}j and S Jarnum and Jensen, {H E} and P Jess and T Justesen and J Kj{\ae}rgaard and P Klarskov and E Krag and P Madsen and E Magid and A Malchow-M{\o}ller and H Marcussen and P Matzen and B. N{\o}rgaard and O Pedersen-Bjergaard and D Raahave and A Schmidt and B Stigsby and D Teilum and A Uhrenholdt and B Villumsen and K Winkler and {The Copenhagen Pancreatitis Study Group}",

year = "1981",

doi = "10.3109/00365528109181973",

language = "English",

volume = "16",

pages = "305--312",

journal = "Scandinavian Journal of Gastroenterology. Supplement",

issn = "0085-5928",

publisher = "Taylor & Francis",

number = "2",

}

TY - JOUR

T1 - Copenhagen pancreatitis study

T2 - An interim report from a prospective epidemiological multicentre study

AU - Andersen, Jens Rikardt

AU - Backer, O

AU - Balsløv, J T

AU - Bonnevie, O.

AU - Burcharth, F

AU - Christoffersen, I

AU - Christoffersen, P

AU - Clausen, B

AU - Ehlers, D

AU - Fischermann, K

AU - Frederiksen, H J

AU - Friedberg, R

AU - Hamilton, B

AU - Hardt, F

AU - Hegnhøj, J

AU - Jarnum, S

AU - Jensen, H E

AU - Jess, P

AU - Justesen, T

AU - Kjærgaard, J

AU - Klarskov, P

AU - Krag, E

AU - Madsen, P

AU - Magid, E

AU - Malchow-Møller, A

AU - Marcussen, H

AU - Matzen, P

AU - Nørgaard, B.

AU - Pedersen-Bjergaard, O

AU - Raahave, D

AU - Schmidt, A

AU - Stigsby, B

AU - Teilum, D

AU - Uhrenholdt, A

AU - Villumsen, B

AU - Winkler, K

AU - The Copenhagen Pancreatitis Study Group

PY - 1981

Y1 - 1981

N2 - During the past 2 decades an increasing number of patients with pancreatitis have been admitted to the Copenhagen hospitals. For this reason all departments receiving such patients from the city of Copenhagen initiated the Copenhagen Pancreatitis Study (CPS), to provide a prospective recording of all pancreatitis patients from this geographical area and to conduct yearly follow-up studies of the patients. The aims of the CPS were, first, to establish data on the incidence, prevalence, and clinical characteristics of pancreatitis, and, second, to evaluate the accuracy of diagnostic tests applied and to provide data on the natural history and the prognosis under current therapy. The present study is an interim report on 343 patients from the initial 1 1/2 years of the CPS. Pancreatitis patients are listed in four diagnostic groups: I. Possible acute pancreatitis; II. Acute pancreatitis; III. Possible chronic pancreatitis; IV. Chronic pancreatitis. The incidence rates per year per 100,000 citizens aged 20 years or more (population aged 20 years or more: 417,000) were as follows: total, 36.3; I, 6.2; II, 21.9; III, 4.2; IV, 4.0. The prevalence for the chronic types on 31 August 1979 per 100,000 citizens aged 20 years or more was as follows: total, 27.4; III, 14.4; IV, 13.0. Gallstones were found in 1/3 of the acute and 1/10 of the chronic cases. Alcohol consumption was more than 50g/day in nearly half of the patients. Acute pancreatitis was dominated by a high leukocyte count, hyperbilirubinaemia, raised aminotransferases and blood glucose levels, and low albumin and calcium levels in serum. In chronic pancreatitis 1/3 had steatorrhoea; 1/6 regularly used morphine, and 1/4 had impaired liver function. It is concluded that the incidence rates of acute and chronic pancreatitis in Copenhagen seem to be higher than those reported elsewhere; however, differences in diagnostic criteria may play a role. The clinical and laboratory findings are in agreement with other studies.

AB - During the past 2 decades an increasing number of patients with pancreatitis have been admitted to the Copenhagen hospitals. For this reason all departments receiving such patients from the city of Copenhagen initiated the Copenhagen Pancreatitis Study (CPS), to provide a prospective recording of all pancreatitis patients from this geographical area and to conduct yearly follow-up studies of the patients. The aims of the CPS were, first, to establish data on the incidence, prevalence, and clinical characteristics of pancreatitis, and, second, to evaluate the accuracy of diagnostic tests applied and to provide data on the natural history and the prognosis under current therapy. The present study is an interim report on 343 patients from the initial 1 1/2 years of the CPS. Pancreatitis patients are listed in four diagnostic groups: I. Possible acute pancreatitis; II. Acute pancreatitis; III. Possible chronic pancreatitis; IV. Chronic pancreatitis. The incidence rates per year per 100,000 citizens aged 20 years or more (population aged 20 years or more: 417,000) were as follows: total, 36.3; I, 6.2; II, 21.9; III, 4.2; IV, 4.0. The prevalence for the chronic types on 31 August 1979 per 100,000 citizens aged 20 years or more was as follows: total, 27.4; III, 14.4; IV, 13.0. Gallstones were found in 1/3 of the acute and 1/10 of the chronic cases. Alcohol consumption was more than 50g/day in nearly half of the patients. Acute pancreatitis was dominated by a high leukocyte count, hyperbilirubinaemia, raised aminotransferases and blood glucose levels, and low albumin and calcium levels in serum. In chronic pancreatitis 1/3 had steatorrhoea; 1/6 regularly used morphine, and 1/4 had impaired liver function. It is concluded that the incidence rates of acute and chronic pancreatitis in Copenhagen seem to be higher than those reported elsewhere; however, differences in diagnostic criteria may play a role. The clinical and laboratory findings are in agreement with other studies.

KW - Abdomen, acute condition

KW - Alcohol drinking

KW - Amylase

KW - Blood sugar

KW - Calcium

KW - Cholelithiasis

KW - Epidemiology

KW - Liver disease

KW - Morphine

KW - Pancreatic disease

KW - Pancreatitis

KW - Prospective studies

U2 - 10.3109/00365528109181973

DO - 10.3109/00365528109181973

M3 - Journal article

C2 - 7313541

AN - SCOPUS:0019524138

SN - 0085-5928

VL - 16

SP - 305

EP - 312

JO - Scandinavian Journal of Gastroenterology. Supplement

JF - Scandinavian Journal of Gastroenterology. Supplement

IS - 2

ER -

Copenhagen pancreatitis study: An interim report from a prospective epidemiological multicentre study

Abstract

Keywords

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