Control of cell proliferation by Myc.

C Bouchard, P Staller, M Eilers

    200 Citations (Scopus)

    Abstract

    Myc proteins are key regulators of mammalian cell proliferation. They are transcription factors that activate genes as part of a heterodimeric complex with the protein Max. This review summarizes recent progress in understanding how Myc stimulates cell proliferation and how this might contribute to cellular transformation and tumorigenesis.
    Original languageEnglish
    JournalTrends in Cell Biolology
    Volume8
    Issue number5
    Pages (from-to)202-6
    Number of pages4
    ISSN0962-8924
    Publication statusPublished - 1998

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