Contact allergy in children with atopic dermatitis: a systematic review

A. B. Simonsen*, J. D. Johansen, M. Deleuran, C. G. Mortz, M. Sommerlund

*Corresponding author for this work
20 Citations (Scopus)

Abstract

The importance of contact allergy in children with atopic dermatitis is frequently debated. Previously, patients with atopic dermatitis were believed to have a reduced ability to produce a type IV immunological response. However, this belief has been challenged and authors have highlighted the risk of underestimating and overlooking allergic contact dermatitis in children with atopic dermatitis. Several studies have been published aiming to shed light on this important question but results are contradictory. To provide an overview of the existing knowledge, we systematically reviewed studies that report frequencies of positive patch test reactions in children with atopic dermatitis. We identified 436 manuscripts of which 31 met the inclusion criteria. Although the literature is conflicting, it is evident that contact allergy is a common problem in children with atopic dermatitis.

Original languageEnglish
JournalBritish Journal of Dermatology
Volume177
Issue number2
Pages (from-to)395-405
Number of pages11
ISSN0007-0963
DOIs
Publication statusPublished - Aug 2017

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