Constitutive expression of inducible nitric oxide synthase in the normal human colonic epithelium

A Perner; Lars Andresen; M Normark; J Rask-Madsen

Constitutive expression of inducible nitric oxide synthase in the normal human colonic epithelium

A Perner, Lars Andresen, M Normark, J Rask-Madsen

21 Citations (Scopus)

Abstract

Inducible nitric oxide synthase (iNOS) in the human colon is considered expressed only in inflammatory states such as ulcerative or collagenous colitis. As subtle iNOS labelling was previously observed in some colonic mucosal biopsies from a heterogeneous group of controls with non-inflamed bowel, we studied whether bowel preparation with bisacodyl or polyethylene glycol prior to sigmoidoscopy might induce iNOS expression.

Original language	English
Journal	Scandinavian Journal of Gastroenterology
Volume	37
Issue number	8
Pages (from-to)	944-8
Number of pages	5
ISSN	0036-5521
Publication status	Published - 2002

Keywords

Adult
Bisacodyl
Blotting, Western
Cathartics
Colon
Humans
Immunohistochemistry
Intestinal Mucosa
Male
Nitric Oxide Synthase
Nitric Oxide Synthase Type II
Polyethylene Glycols

Cite this

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title = "Constitutive expression of inducible nitric oxide synthase in the normal human colonic epithelium",

abstract = "Inducible nitric oxide synthase (iNOS) in the human colon is considered expressed only in inflammatory states such as ulcerative or collagenous colitis. As subtle iNOS labelling was previously observed in some colonic mucosal biopsies from a heterogeneous group of controls with non-inflamed bowel, we studied whether bowel preparation with bisacodyl or polyethylene glycol prior to sigmoidoscopy might induce iNOS expression.",

keywords = "Adult, Bisacodyl, Blotting, Western, Cathartics, Colon, Humans, Immunohistochemistry, Intestinal Mucosa, Male, Nitric Oxide Synthase, Nitric Oxide Synthase Type II, Polyethylene Glycols",

author = "A Perner and Lars Andresen and M Normark and J Rask-Madsen",

year = "2002",

language = "English",

volume = "37",

pages = "944--8",

journal = "Scandinavian Journal of Gastroenterology",

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TY - JOUR

T1 - Constitutive expression of inducible nitric oxide synthase in the normal human colonic epithelium

AU - Perner, A

AU - Andresen, Lars

AU - Normark, M

AU - Rask-Madsen, J

PY - 2002

Y1 - 2002

N2 - Inducible nitric oxide synthase (iNOS) in the human colon is considered expressed only in inflammatory states such as ulcerative or collagenous colitis. As subtle iNOS labelling was previously observed in some colonic mucosal biopsies from a heterogeneous group of controls with non-inflamed bowel, we studied whether bowel preparation with bisacodyl or polyethylene glycol prior to sigmoidoscopy might induce iNOS expression.

AB - Inducible nitric oxide synthase (iNOS) in the human colon is considered expressed only in inflammatory states such as ulcerative or collagenous colitis. As subtle iNOS labelling was previously observed in some colonic mucosal biopsies from a heterogeneous group of controls with non-inflamed bowel, we studied whether bowel preparation with bisacodyl or polyethylene glycol prior to sigmoidoscopy might induce iNOS expression.

KW - Adult

KW - Bisacodyl

KW - Blotting, Western

KW - Cathartics

KW - Colon

KW - Humans

KW - Immunohistochemistry

KW - Intestinal Mucosa

KW - Male

KW - Nitric Oxide Synthase

KW - Nitric Oxide Synthase Type II

KW - Polyethylene Glycols

M3 - Journal article

C2 - 12229970

SN - 0036-5521

VL - 37

SP - 944

EP - 948

JO - Scandinavian Journal of Gastroenterology

JF - Scandinavian Journal of Gastroenterology

IS - 8

ER -

Constitutive expression of inducible nitric oxide synthase in the normal human colonic epithelium

Abstract

Keywords

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