Confirmatory factor analysis of the Neuropsychological Assessment Battery of the LADIS study: A longitudinal analysis

Carla Moleiro; Sofia Madureira; Ana Verdelho; José M Ferro; Anna Poggesi; Hugues Chabriat; Timo Erkinjuntti; Franz Fazekas; Michael Hennerici; John O'Brien; Leonardo Pantoni; Emilia Salvadori; Philip Scheltens; Marieke C Visser; Lars-Olof Wahlund; Gunhild Waldemar; Anders Wallin; Domenico Inzitari; LADIS Study

doi:10.1080/13803395.2013.770822

Confirmatory factor analysis of the Neuropsychological Assessment Battery of the LADIS study: A longitudinal analysis

Carla Moleiro, Sofia Madureira, Ana Verdelho, José M Ferro, Anna Poggesi, Hugues Chabriat, Timo Erkinjuntti, Franz Fazekas, Michael Hennerici, John O'Brien, Leonardo Pantoni, Emilia Salvadori, Philip Scheltens, Marieke C Visser, Lars-Olof Wahlund, Gunhild Waldemar, Anders Wallin, Domenico Inzitari, LADIS Study

Department of Clinical Medicine

9 Citations (Scopus)

Abstract

Age-related white matter changes have been associated with cognitive functioning, even though their role is not fully understood. This work aimed to test a 3-factor model of the neuropsychological assessment battery and evaluate how the model fit the data longitudinally. Confirmatory factor analysis (CFA) was used to investigate the dimensions of a structured set of neuropsychological tests administered to a multicenter, international sample of independent older adults (LADIS study). Six hundred and thirty-eight older adults completed baseline neuropsychological, clinical, functional and motor assessments, which were repeated each year for a 3-year follow-up. CFA provided support for a 3-factor model. These factors involve the dimensions of executive functions, memory functions, and speed and motor control abilities. Performance decreased in most neuropsychological measures. Results showed that executive functioning, memory and speed of motor abilities are valid latent variables of neuropsychological performance among older adults, and that this structure is relatively consistent longitudinally, even though performance decreases with time.

Original language	English
Journal	Journal of Clinical and Experimental Neuropsychology
Volume	35
Issue number	3
Pages (from-to)	269-278
Number of pages	10
ISSN	1380-3395
DOIs	https://doi.org/10.1080/13803395.2013.770822
Publication status	Published - 1 Mar 2013

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Moleiro, C., Madureira, S., Verdelho, A., Ferro, J. M., Poggesi, A., Chabriat, H., Erkinjuntti, T., Fazekas, F., Hennerici, M., O'Brien, J., Pantoni, L., Salvadori, E., Scheltens, P., Visser, M. C., Wahlund, L-O., Waldemar, G., Wallin, A., Inzitari, D., & Study, LADIS. (2013). Confirmatory factor analysis of the Neuropsychological Assessment Battery of the LADIS study: A longitudinal analysis. Journal of Clinical and Experimental Neuropsychology, 35(3), 269-278. https://doi.org/10.1080/13803395.2013.770822

Moleiro, C, Madureira, S, Verdelho, A, Ferro, JM, Poggesi, A, Chabriat, H, Erkinjuntti, T, Fazekas, F, Hennerici, M, O'Brien, J, Pantoni, L, Salvadori, E, Scheltens, P, Visser, MC, Wahlund, L-O, Waldemar, G, Wallin, A, Inzitari, D & Study, LADIS 2013, 'Confirmatory factor analysis of the Neuropsychological Assessment Battery of the LADIS study: A longitudinal analysis', Journal of Clinical and Experimental Neuropsychology, vol. 35, no. 3, pp. 269-278. https://doi.org/10.1080/13803395.2013.770822

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abstract = "Age-related white matter changes have been associated with cognitive functioning, even though their role is not fully understood. This work aimed to test a 3-factor model of the neuropsychological assessment battery and evaluate how the model fit the data longitudinally. Confirmatory factor analysis (CFA) was used to investigate the dimensions of a structured set of neuropsychological tests administered to a multicenter, international sample of independent older adults (LADIS study). Six hundred and thirty-eight older adults completed baseline neuropsychological, clinical, functional and motor assessments, which were repeated each year for a 3-year follow-up. CFA provided support for a 3-factor model. These factors involve the dimensions of executive functions, memory functions, and speed and motor control abilities. Performance decreased in most neuropsychological measures. Results showed that executive functioning, memory and speed of motor abilities are valid latent variables of neuropsychological performance among older adults, and that this structure is relatively consistent longitudinally, even though performance decreases with time.",

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AU - Moleiro, Carla

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AU - Ferro, José M

AU - Poggesi, Anna

AU - Chabriat, Hugues

AU - Erkinjuntti, Timo

AU - Fazekas, Franz

AU - Hennerici, Michael

AU - O'Brien, John

AU - Pantoni, Leonardo

AU - Salvadori, Emilia

AU - Scheltens, Philip

AU - Visser, Marieke C

AU - Wahlund, Lars-Olof

AU - Waldemar, Gunhild

AU - Wallin, Anders

AU - Inzitari, Domenico

AU - Study, LADIS

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AB - Age-related white matter changes have been associated with cognitive functioning, even though their role is not fully understood. This work aimed to test a 3-factor model of the neuropsychological assessment battery and evaluate how the model fit the data longitudinally. Confirmatory factor analysis (CFA) was used to investigate the dimensions of a structured set of neuropsychological tests administered to a multicenter, international sample of independent older adults (LADIS study). Six hundred and thirty-eight older adults completed baseline neuropsychological, clinical, functional and motor assessments, which were repeated each year for a 3-year follow-up. CFA provided support for a 3-factor model. These factors involve the dimensions of executive functions, memory functions, and speed and motor control abilities. Performance decreased in most neuropsychological measures. Results showed that executive functioning, memory and speed of motor abilities are valid latent variables of neuropsychological performance among older adults, and that this structure is relatively consistent longitudinally, even though performance decreases with time.

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DO - 10.1080/13803395.2013.770822

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C2 - 23398381

SN - 1380-3395

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JO - Journal of Clinical and Experimental Neuropsychology

JF - Journal of Clinical and Experimental Neuropsychology

IS - 3

ER -

Confirmatory factor analysis of the Neuropsychological Assessment Battery of the LADIS study: A longitudinal analysis

Abstract

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