Comparison of three different weight maintenance programs on cardiovascular risk, bone, and vitamins in sedentary older adults

Pia Christensen; Rikke Frederiksen; Henning Bliddal; Birgit F Riecke; Else M Bartels; Marius Henriksen; Tina Juul-Sørensen; Henrik Gudbergsen; Kaj Winther; Arne Astrup; Robin Christensen

doi:10.1002/oby.20413

Comparison of three different weight maintenance programs on cardiovascular risk, bone, and vitamins in sedentary older adults

Pia Christensen, Rikke Frederiksen, Henning Bliddal, Birgit F Riecke, Else M Bartels, Marius Henriksen, Tina Juul-Sørensen, Henrik Gudbergsen, Kaj Winther, Arne Astrup, Robin Christensen

24 Citations (Scopus)

Abstract

OBJECTIVE: Obese patients with knee osteoarthritis (OA) are encouraged to lose weight to obtain symptomatic relief. Risk of vascular events is higher in people with OA compared to people without arthritis. Our aim in this randomized trial was to compare changes in cardiovascular disease (CVD) risk-factors, nutritional health, and body composition after 1-year weight-loss maintenance achieved by [D]diet, [E]knee-exercise, or [C]control, following weight loss by low-energy-diet. DESIGN AND METHODS: Obese individuals (n = 192, >50 years) with knee OA, 63 years (SD 6), weight 103.2 kg (15.0), body-mass index 37.3 kg/m(2) (4.8), were enrolled into a 68-week weight-loss trial. RESULTS: Mean changes in weight, in D, E, and C were -11.0, -6.3, and -8.3 kg (P = 0.002). Reduction in waist circumference in D, E, and C were -8.4, -4.6, and -7.0 cm (P = 0.007). D reduced waist circumference significantly more than E: -3.8 cm (95%CI -6.2 to -1.4; P = 0.0024). There was no difference between the groups in changes in CVD risk factors; blood pressure, triglycerides, and cholesterol. Nutritional health was improved in all groups. For markers of bone, no statistical difference was found between the groups. CONCLUSIONS: Dietary support, or control, maintained improvements in cardiovascular risk factors to the same extent and none of the interventions had a detrimental effect on bone.

Original language	English
Journal	Obesity
Volume	21
Issue number	10
Pages (from-to)	1982-1990
Number of pages	9
ISSN	1930-7381
DOIs	https://doi.org/10.1002/oby.20413
Publication status	Published - Oct 2013

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10.1002/oby.20413

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@article{0aae71284c4d434da92cd730ac9ce7fa,

title = "Comparison of three different weight maintenance programs on cardiovascular risk, bone, and vitamins in sedentary older adults",

abstract = "OBJECTIVE: Obese patients with knee osteoarthritis (OA) are encouraged to lose weight to obtain symptomatic relief. Risk of vascular events is higher in people with OA compared to people without arthritis. Our aim in this randomized trial was to compare changes in cardiovascular disease (CVD) risk-factors, nutritional health, and body composition after 1-year weight-loss maintenance achieved by [D]diet, [E]knee-exercise, or [C]control, following weight loss by low-energy-diet. DESIGN AND METHODS: Obese individuals (n = 192, >50 years) with knee OA, 63 years (SD 6), weight 103.2 kg (15.0), body-mass index 37.3 kg/m(2) (4.8), were enrolled into a 68-week weight-loss trial. RESULTS: Mean changes in weight, in D, E, and C were -11.0, -6.3, and -8.3 kg (P = 0.002). Reduction in waist circumference in D, E, and C were -8.4, -4.6, and -7.0 cm (P = 0.007). D reduced waist circumference significantly more than E: -3.8 cm (95%CI -6.2 to -1.4; P = 0.0024). There was no difference between the groups in changes in CVD risk factors; blood pressure, triglycerides, and cholesterol. Nutritional health was improved in all groups. For markers of bone, no statistical difference was found between the groups. CONCLUSIONS: Dietary support, or control, maintained improvements in cardiovascular risk factors to the same extent and none of the interventions had a detrimental effect on bone.",

author = "Pia Christensen and Rikke Frederiksen and Henning Bliddal and Riecke, {Birgit F} and Bartels, {Else M} and Marius Henriksen and Tina Juul-S{\o}rensen and Henrik Gudbergsen and Kaj Winther and Arne Astrup and Robin Christensen",

note = "CURIS 2013 NEXS 081",

year = "2013",

month = oct,

doi = "10.1002/oby.20413",

language = "English",

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pages = "1982--1990",

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T1 - Comparison of three different weight maintenance programs on cardiovascular risk, bone, and vitamins in sedentary older adults

AU - Christensen, Pia

AU - Frederiksen, Rikke

AU - Bliddal, Henning

AU - Riecke, Birgit F

AU - Bartels, Else M

AU - Henriksen, Marius

AU - Juul-Sørensen, Tina

AU - Gudbergsen, Henrik

AU - Winther, Kaj

AU - Astrup, Arne

AU - Christensen, Robin

N1 - CURIS 2013 NEXS 081

PY - 2013/10

Y1 - 2013/10

N2 - OBJECTIVE: Obese patients with knee osteoarthritis (OA) are encouraged to lose weight to obtain symptomatic relief. Risk of vascular events is higher in people with OA compared to people without arthritis. Our aim in this randomized trial was to compare changes in cardiovascular disease (CVD) risk-factors, nutritional health, and body composition after 1-year weight-loss maintenance achieved by [D]diet, [E]knee-exercise, or [C]control, following weight loss by low-energy-diet. DESIGN AND METHODS: Obese individuals (n = 192, >50 years) with knee OA, 63 years (SD 6), weight 103.2 kg (15.0), body-mass index 37.3 kg/m(2) (4.8), were enrolled into a 68-week weight-loss trial. RESULTS: Mean changes in weight, in D, E, and C were -11.0, -6.3, and -8.3 kg (P = 0.002). Reduction in waist circumference in D, E, and C were -8.4, -4.6, and -7.0 cm (P = 0.007). D reduced waist circumference significantly more than E: -3.8 cm (95%CI -6.2 to -1.4; P = 0.0024). There was no difference between the groups in changes in CVD risk factors; blood pressure, triglycerides, and cholesterol. Nutritional health was improved in all groups. For markers of bone, no statistical difference was found between the groups. CONCLUSIONS: Dietary support, or control, maintained improvements in cardiovascular risk factors to the same extent and none of the interventions had a detrimental effect on bone.

AB - OBJECTIVE: Obese patients with knee osteoarthritis (OA) are encouraged to lose weight to obtain symptomatic relief. Risk of vascular events is higher in people with OA compared to people without arthritis. Our aim in this randomized trial was to compare changes in cardiovascular disease (CVD) risk-factors, nutritional health, and body composition after 1-year weight-loss maintenance achieved by [D]diet, [E]knee-exercise, or [C]control, following weight loss by low-energy-diet. DESIGN AND METHODS: Obese individuals (n = 192, >50 years) with knee OA, 63 years (SD 6), weight 103.2 kg (15.0), body-mass index 37.3 kg/m(2) (4.8), were enrolled into a 68-week weight-loss trial. RESULTS: Mean changes in weight, in D, E, and C were -11.0, -6.3, and -8.3 kg (P = 0.002). Reduction in waist circumference in D, E, and C were -8.4, -4.6, and -7.0 cm (P = 0.007). D reduced waist circumference significantly more than E: -3.8 cm (95%CI -6.2 to -1.4; P = 0.0024). There was no difference between the groups in changes in CVD risk factors; blood pressure, triglycerides, and cholesterol. Nutritional health was improved in all groups. For markers of bone, no statistical difference was found between the groups. CONCLUSIONS: Dietary support, or control, maintained improvements in cardiovascular risk factors to the same extent and none of the interventions had a detrimental effect on bone.

U2 - 10.1002/oby.20413

DO - 10.1002/oby.20413

M3 - Journal article

C2 - 23512743

SN - 1930-7381

VL - 21

SP - 1982

EP - 1990

JO - Obesity

JF - Obesity

IS - 10

ER -

Comparison of three different weight maintenance programs on cardiovascular risk, bone, and vitamins in sedentary older adults

Abstract

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