Comorbidity and mortality after hip fracture in nineteen thousand six hundred and eighty two patients aged eighteen to sixty five years in Denmark from 1996 to 2012

Adam Omari; Christian Medom Madsen; Jes Bruun Lauritzen; Henrik Løvendahl Jørgensen; Fie Juhl Vojdeman

doi:10.1007/s00264-019-04323-z

Comorbidity and mortality after hip fracture in nineteen thousand six hundred and eighty two patients aged eighteen to sixty five years in Denmark from 1996 to 2012

Adam Omari, Christian Medom Madsen, Jes Bruun Lauritzen, Henrik Løvendahl Jørgensen, Fie Juhl Vojdeman^*

^*Corresponding author for this work

9 Citations (Scopus)

Abstract

Purpose: This nationwide study assessed associations between comorbidity and mortality after hip fracture in young and middle-aged patients. Methods: Data on 19,682 patients aged 18 to 65 years were extracted from Danish registries out of 154,047 patients who experienced a hip fracture between 1996 and 2012. Mortality and comorbidity were assessed using information on vital status, hospital admissions, and prescriptions. Results: Of the 19,682 patients 17,722 (90.0%) were middle-aged (40–65 years) and 1960 (10.0%) were young (18–39 years). The 30-day mortality rates were 3.2% (n = 570) and 1.6% (n = 32), respectively. Indicators of multi-trauma (hazard ratio (HR), 3.5 95% confidence interval (CI) [1.6–7.8], n = 2056) and having diabetes (HR, 4.4 [1.2–11.3], n = 59) and heart disease (HR, 4.4[1.3–14.8], n = 57) increased 30-day mortality in the young patients, while having cancer (HR, 5.0 [4.2–5.9], n = 1958) increased 30-day mortality in the middle-aged patients. Conclusion: Heart disease and diabetes were associated with high mortality in the young patients while having cancer was associated with high mortality in the middle-aged patients.

Original language	English
Journal	International Orthopaedics
ISSN	0341-2695
DOIs	https://doi.org/10.1007/s00264-019-04323-z
Publication status	Published - 1 Nov 2019

Keywords

Age
Comorbidity
Diabetes
Heart disease
Hip fracture

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This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1007/s00264-019-04323-z

Cite this

@article{04328ca02c8043e1b151b518a65e0501,

title = "Comorbidity and mortality after hip fracture in nineteen thousand six hundred and eighty two patients aged eighteen to sixty five years in Denmark from 1996 to 2012",

abstract = "Purpose: This nationwide study assessed associations between comorbidity and mortality after hip fracture in young and middle-aged patients. Methods: Data on 19,682 patients aged 18 to 65 years were extracted from Danish registries out of 154,047 patients who experienced a hip fracture between 1996 and 2012. Mortality and comorbidity were assessed using information on vital status, hospital admissions, and prescriptions. Results: Of the 19,682 patients 17,722 (90.0%) were middle-aged (40–65 years) and 1960 (10.0%) were young (18–39 years). The 30-day mortality rates were 3.2% (n = 570) and 1.6% (n = 32), respectively. Indicators of multi-trauma (hazard ratio (HR), 3.5 95% confidence interval (CI) [1.6–7.8], n = 2056) and having diabetes (HR, 4.4 [1.2–11.3], n = 59) and heart disease (HR, 4.4[1.3–14.8], n = 57) increased 30-day mortality in the young patients, while having cancer (HR, 5.0 [4.2–5.9], n = 1958) increased 30-day mortality in the middle-aged patients. Conclusion: Heart disease and diabetes were associated with high mortality in the young patients while having cancer was associated with high mortality in the middle-aged patients.",

keywords = "Age, Comorbidity, Diabetes, Heart disease, Hip fracture",

author = "Adam Omari and Madsen, {Christian Medom} and Lauritzen, {Jes Bruun} and J{\o}rgensen, {Henrik L{\o}vendahl} and Vojdeman, {Fie Juhl}",

year = "2019",

month = nov,

day = "1",

doi = "10.1007/s00264-019-04323-z",

language = "English",

journal = "International Orthopaedics",

issn = "0341-2695",

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TY - JOUR

T1 - Comorbidity and mortality after hip fracture in nineteen thousand six hundred and eighty two patients aged eighteen to sixty five years in Denmark from 1996 to 2012

AU - Omari, Adam

AU - Madsen, Christian Medom

AU - Lauritzen, Jes Bruun

AU - Jørgensen, Henrik Løvendahl

AU - Vojdeman, Fie Juhl

PY - 2019/11/1

Y1 - 2019/11/1

N2 - Purpose: This nationwide study assessed associations between comorbidity and mortality after hip fracture in young and middle-aged patients. Methods: Data on 19,682 patients aged 18 to 65 years were extracted from Danish registries out of 154,047 patients who experienced a hip fracture between 1996 and 2012. Mortality and comorbidity were assessed using information on vital status, hospital admissions, and prescriptions. Results: Of the 19,682 patients 17,722 (90.0%) were middle-aged (40–65 years) and 1960 (10.0%) were young (18–39 years). The 30-day mortality rates were 3.2% (n = 570) and 1.6% (n = 32), respectively. Indicators of multi-trauma (hazard ratio (HR), 3.5 95% confidence interval (CI) [1.6–7.8], n = 2056) and having diabetes (HR, 4.4 [1.2–11.3], n = 59) and heart disease (HR, 4.4[1.3–14.8], n = 57) increased 30-day mortality in the young patients, while having cancer (HR, 5.0 [4.2–5.9], n = 1958) increased 30-day mortality in the middle-aged patients. Conclusion: Heart disease and diabetes were associated with high mortality in the young patients while having cancer was associated with high mortality in the middle-aged patients.

AB - Purpose: This nationwide study assessed associations between comorbidity and mortality after hip fracture in young and middle-aged patients. Methods: Data on 19,682 patients aged 18 to 65 years were extracted from Danish registries out of 154,047 patients who experienced a hip fracture between 1996 and 2012. Mortality and comorbidity were assessed using information on vital status, hospital admissions, and prescriptions. Results: Of the 19,682 patients 17,722 (90.0%) were middle-aged (40–65 years) and 1960 (10.0%) were young (18–39 years). The 30-day mortality rates were 3.2% (n = 570) and 1.6% (n = 32), respectively. Indicators of multi-trauma (hazard ratio (HR), 3.5 95% confidence interval (CI) [1.6–7.8], n = 2056) and having diabetes (HR, 4.4 [1.2–11.3], n = 59) and heart disease (HR, 4.4[1.3–14.8], n = 57) increased 30-day mortality in the young patients, while having cancer (HR, 5.0 [4.2–5.9], n = 1958) increased 30-day mortality in the middle-aged patients. Conclusion: Heart disease and diabetes were associated with high mortality in the young patients while having cancer was associated with high mortality in the middle-aged patients.

KW - Age

KW - Comorbidity

KW - Diabetes

KW - Heart disease

KW - Hip fracture

U2 - 10.1007/s00264-019-04323-z

DO - 10.1007/s00264-019-04323-z

M3 - Journal article

C2 - 30903256

AN - SCOPUS:85064074220

SN - 0341-2695

JO - International Orthopaedics

JF - International Orthopaedics