Common Sense Approach to Managing Sepsis

TY - JOUR

T1 - Common Sense Approach to Managing Sepsis

AU - Perner, Anders

AU - Holst, Lars B.

AU - Haase, Nicolai

AU - Hjortrup, Peter B.

AU - Møller, Morten H.

PY - 2018

Y1 - 2018

N2 - Sepsis results in many deaths, prolonged suffering among survivors and relatives, and high use of resources both in developed and developing countries. The updated Surviving Sepsis Campaign guidelines should aid clinicians in improving the identification and management of these patients, but many uncertainties remain because most of the guidance is based on low-quality evidence. This article discusses how to use some of the specific items of the guidelines together with a common-sense approach to aid clinical management of patients with sepsis while trying to balance the potential benefit and harm of the items.

AB - Sepsis results in many deaths, prolonged suffering among survivors and relatives, and high use of resources both in developed and developing countries. The updated Surviving Sepsis Campaign guidelines should aid clinicians in improving the identification and management of these patients, but many uncertainties remain because most of the guidance is based on low-quality evidence. This article discusses how to use some of the specific items of the guidelines together with a common-sense approach to aid clinical management of patients with sepsis while trying to balance the potential benefit and harm of the items.

KW - Antibiotics

KW - Critical care

KW - Fluids

KW - Hemodynamic monitoring

KW - Resuscitation

KW - Sepsis

U2 - 10.1016/j.ccc.2017.08.009

DO - 10.1016/j.ccc.2017.08.009

M3 - Review

C2 - 29149934

AN - SCOPUS:85030750211

SN - 0749-0704

VL - 34

SP - 127

EP - 138

JO - Critical Care Clinics

JF - Critical Care Clinics

IS - 1

ER -