Commercial Antibodies: The Good, Bad, and Really Ugly.

TY - JOUR

T1 - Commercial Antibodies: The Good, Bad, and Really Ugly.

AU - Couchman, John R

PY - 2008

Y1 - 2008

N2 - The range of antibodies available commercially grows ever larger. Perhaps as a consequence, quality control is not always what it could and should be. Investigators must be aware of potential pitfalls and take steps to assure themselves that the specificity of each antibody is as advertised. Additionally, companies should provide the necessary information about the antigen and antibody to investigators, including references, so that the appropriate controls can be included.

AB - The range of antibodies available commercially grows ever larger. Perhaps as a consequence, quality control is not always what it could and should be. Investigators must be aware of potential pitfalls and take steps to assure themselves that the specificity of each antibody is as advertised. Additionally, companies should provide the necessary information about the antigen and antibody to investigators, including references, so that the appropriate controls can be included.

U2 - 10.1369/jhc.2008.952820

DO - 10.1369/jhc.2008.952820

M3 - Comment/debate

C2 - 18854593

SN - 0022-1554

JO - Journal of Histochemistry and Cytochemistry

JF - Journal of Histochemistry and Cytochemistry

ER -