Combining traditional dietary assessment methods with novel metabolomics techniques: present efforts by the Food Biomarker Alliance

TY - JOUR

T1 - Combining traditional dietary assessment methods with novel metabolomics techniques

T2 - Nutrition Society Summer Meeting

AU - Brouwer-Brolsma, Elske M

AU - Brennan, Lorraine

AU - Drevon, Christian A

AU - van Kranen, Henk

AU - Manach, Claudine

AU - Dragsted, Lars Ove

AU - Roche, Helen M

AU - Andres-Lacueva, Cristina

AU - Bakker, Stephan J L

AU - Bouwman, Jildau

AU - Capozzi, Francesco

AU - De Saeger, Sarah

AU - Gundersen, Thomas E

AU - Kolehmainen, Marjukka

AU - Kulling, Sabine E

AU - Landberg, Rikard

AU - Linseisen, Jakob

AU - Mattivi, Fulvio

AU - Mensink, Ronald P

AU - Scaccini, Cristina

AU - Skurk, Thomas

AU - Tetens, Inge

AU - Vergeres, Guy

AU - Wishart, David S

AU - Scalbert, Augustin

AU - Feskens, Edith J M

N1 - CURIS 2017 NEXS 314

PY - 2017/11/1

Y1 - 2017/11/1

N2 - FFQ, food diaries and 24 h recall methods represent the most commonly used dietary assessment tools in human studies on nutrition and health, but food intake biomarkers are assumed to provide a more objective reflection of intake. Unfortunately, very few of these biomarkers are sufficiently validated. This review provides an overview of food intake biomarker research and highlights present research efforts of the Joint Programming Initiative 'A Healthy Diet for a Healthy Life' (JPI-HDHL) Food Biomarkers Alliance (FoodBAll). In order to identify novel food intake biomarkers, the focus is on new food metabolomics techniques that allow the quantification of up to thousands of metabolites simultaneously, which may be applied in intervention and observational studies. As biomarkers are often influenced by various other factors than the food under investigation, FoodBAll developed a food intake biomarker quality and validity score aiming to assist the systematic evaluation of novel biomarkers. Moreover, to evaluate the applicability of nutritional biomarkers, studies are presently also focusing on associations between food intake biomarkers and diet-related disease risk. In order to be successful in these metabolomics studies, knowledge about available electronic metabolomics resources is necessary and further developments of these resources are essential. Ultimately, present efforts in this research area aim to advance quality control of traditional dietary assessment methods, advance compliance evaluation in nutritional intervention studies, and increase the significance of observational studies by investigating associations between nutrition and health.

AB - FFQ, food diaries and 24 h recall methods represent the most commonly used dietary assessment tools in human studies on nutrition and health, but food intake biomarkers are assumed to provide a more objective reflection of intake. Unfortunately, very few of these biomarkers are sufficiently validated. This review provides an overview of food intake biomarker research and highlights present research efforts of the Joint Programming Initiative 'A Healthy Diet for a Healthy Life' (JPI-HDHL) Food Biomarkers Alliance (FoodBAll). In order to identify novel food intake biomarkers, the focus is on new food metabolomics techniques that allow the quantification of up to thousands of metabolites simultaneously, which may be applied in intervention and observational studies. As biomarkers are often influenced by various other factors than the food under investigation, FoodBAll developed a food intake biomarker quality and validity score aiming to assist the systematic evaluation of novel biomarkers. Moreover, to evaluate the applicability of nutritional biomarkers, studies are presently also focusing on associations between food intake biomarkers and diet-related disease risk. In order to be successful in these metabolomics studies, knowledge about available electronic metabolomics resources is necessary and further developments of these resources are essential. Ultimately, present efforts in this research area aim to advance quality control of traditional dietary assessment methods, advance compliance evaluation in nutritional intervention studies, and increase the significance of observational studies by investigating associations between nutrition and health.

KW - Dietary assessment

KW - Food intake biomarkers

KW - Food metabolome

KW - Metabolomics

U2 - 10.1017/s0029665117003949

DO - 10.1017/s0029665117003949

M3 - Journal article

C2 - 29137687

SN - 0029-6651

VL - 76

SP - 619

EP - 627

JO - Proceedings of the Nutrition Society

JF - Proceedings of the Nutrition Society

IS - 4

Y2 - 11 July 2016 through 14 July 2016

ER -