TY - JOUR
T1 - Climatic influences on development and survival of free-living stages of equine strongyles
T2 - implications for worm control strategies and managing anthelmintic resistant
AU - Nielsen, Martin Krarup
AU - Kaplan, Ray M.
AU - Thamsborg, Stig Milan
AU - Monrad, Jesper
AU - Olsen, Susanne Nautrup
PY - 2007
Y1 - 2007
N2 - Development of resistance to anthelmintic drugs by horse strongyles constitutes a growing threat to equine health because it is unknown when the new drug xlasses can be exoected on the market. Consequently, parasite control strategies should attemt to maintain drug efficacy for as long as possible. The proportion of the parasite pupulation that is not exposed to anthelmintic treatment is descriebed as being "in refugia" and althogt many factors affect the rate at which resistance develops, levels of refugia are considered the most important as these parasites are not selected by treatment and so provide a pool of sensitive genes in the population.
AB - Development of resistance to anthelmintic drugs by horse strongyles constitutes a growing threat to equine health because it is unknown when the new drug xlasses can be exoected on the market. Consequently, parasite control strategies should attemt to maintain drug efficacy for as long as possible. The proportion of the parasite pupulation that is not exposed to anthelmintic treatment is descriebed as being "in refugia" and althogt many factors affect the rate at which resistance develops, levels of refugia are considered the most important as these parasites are not selected by treatment and so provide a pool of sensitive genes in the population.
KW - Former LIFE faculty
KW - Strongyles; horse; Refugia; Climate; Anthelmintic resistance
U2 - 10.1016/j.tvjl.2006.05.009
DO - 10.1016/j.tvjl.2006.05.009
M3 - Journal article
SN - 1090-0233
VL - 174
SP - 23
EP - 32
JO - The Veterinary Journal
JF - The Veterinary Journal
IS - 1
ER -