Cirkulerende tumorceller kan muligvis benyttes som prognostisk og prædiktiv markør ved ventrikelcancer

TY - JOUR

T1 - Cirkulerende tumorceller kan muligvis benyttes som prognostisk og prædiktiv markør ved ventrikelcancer

AU - Okholm, Cecilie

AU - Thorsteinsson, Morten

AU - Achiam, Michael Patrick

PY - 2014/8/4

Y1 - 2014/8/4

N2 - Despite chemotherapy and intended curative surgery, approximately 50% of patients with gastric cancer develop recurrence and eventually die of metastatic disease. The detection of circulating tumour cells (CTC) in peripheral blood is a promising prognostic and predictive marker. The most typically applied approaches to the detection of CTC are RT-PCR and immunological assays. Measurement of CTC in gastric cancer seems useful for predicting prognosis and monitoring response of chemotherapy. There is still no gold standard for CTC-detection in gastric cancer patients and larger studies are needed.

AB - Despite chemotherapy and intended curative surgery, approximately 50% of patients with gastric cancer develop recurrence and eventually die of metastatic disease. The detection of circulating tumour cells (CTC) in peripheral blood is a promising prognostic and predictive marker. The most typically applied approaches to the detection of CTC are RT-PCR and immunological assays. Measurement of CTC in gastric cancer seems useful for predicting prognosis and monitoring response of chemotherapy. There is still no gold standard for CTC-detection in gastric cancer patients and larger studies are needed.

M3 - Tidsskriftartikel

C2 - 25292471

SN - 0041-5782

VL - 176

SP - 1490

EP - 1493

JO - Ugeskrift for Laeger

JF - Ugeskrift for Laeger

IS - 16

M1 - V01130083

ER -