Cilia and flagella

TY - ENCYC

T1 - Cilia and flagella

AU - Schmid, Fabian Marc

AU - Christensen, Søren Tvorup

AU - Pedersen, Lotte Bang

PY - 2016

Y1 - 2016

N2 - Cilia and flagella are microtubule-based, rod-shaped organelles present on the surface of a variety of eukaryotic cells. They function in cell locomotion, flow of extracellular fluid across cell surfaces as well as in perception and integration of signals from the cellular surroundings. In vertebrates, cilia are critical for regulating developmental processes and tissue homeostasis. Consequently, genetic defects that impair ciliary function or assembly lead to a growing number of different human diseases. This class of diseases, called ciliopathies, is often pleiotropic affecting multiple organs and tissues in the body.

AB - Cilia and flagella are microtubule-based, rod-shaped organelles present on the surface of a variety of eukaryotic cells. They function in cell locomotion, flow of extracellular fluid across cell surfaces as well as in perception and integration of signals from the cellular surroundings. In vertebrates, cilia are critical for regulating developmental processes and tissue homeostasis. Consequently, genetic defects that impair ciliary function or assembly lead to a growing number of different human diseases. This class of diseases, called ciliopathies, is often pleiotropic affecting multiple organs and tissues in the body.

U2 - 10.1016/B978-0-12-394447-4.20064-3

DO - 10.1016/B978-0-12-394447-4.20064-3

M3 - Encyclopedia chapter

VL - 2

SP - 660

EP - 676

BT - Encyclopedia of cell biology

A2 - Bradshaw, Ralph A.

A2 - Stahl, Philip D.

PB - Elsevier

ER -