CIED infection with either pocket or systemic infection presentation: Complete device removal and long-term antibiotic treatment; long-term outcome

Nikolaj Ihlemann; Michael Møller-Hansen; Kirsten Salado-Rasmussen; Regitze Videbæk; Claus Moser; Kasper Iversen; Henning Bundgaard

doi:10.3109/14017431.2015.1091089

CIED infection with either pocket or systemic infection presentation: Complete device removal and long-term antibiotic treatment; long-term outcome

Nikolaj Ihlemann, Michael Møller-Hansen, Kirsten Salado-Rasmussen, Regitze Videbæk, Claus Moser, Kasper Iversen, Henning Bundgaard

2 Citations (Scopus)

Abstract

OBJECTIVE: Cardiovascular implantable electronic device (CIED) infections are increasing in numbers. The objective was to review the clinical presentation and outcome in patients affected with CIED infections with either local pocket or systemic presentation.

DESIGN: All device removals due to CIED infection during the period from 2005 to 2012 were retrospectively reviewed. CIED infections were categorized as systemic or pocket infections. Treatment included complete removal of the device, followed by antibiotic treatment of six weeks.

RESULTS: Seventy-one device removals due to infection (32 systemic and 39 pocket infections) were recorded during the study period. Median follow-up time was 26 (IQR 9-41) months, 30 day and 12 month mortality were 4% and 14%, respectively. There was no long-term difference in mortality between patients with pocket vs. systemic infection (p = 0.48). During follow-up no relapses and two cases of new infections were noted (2.8%).

CONCLUSIONS: CIED infection with systemic or pocket infection was difficult to distinguish in clinical presentation and outcome. Complete device removal and antibiotic treatment of long duration was safe and without relapses.

Original language	English
Journal	Scandinavian Cardiovascular Journal
Volume	50
Issue number	1
Pages (from-to)	52-7
Number of pages	6
ISSN	1401-7431
DOIs	https://doi.org/10.3109/14017431.2015.1091089
Publication status	Published - 1 Jan 2016

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10.3109/14017431.2015.1091089

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CIED infection with either pocket or systemic infection presentation: Complete device removal and long-term antibiotic treatment; long-term outcome. / Ihlemann, Nikolaj; Møller-Hansen, Michael; Salado-Rasmussen, Kirsten et al.
In: Scandinavian Cardiovascular Journal, Vol. 50, No. 1, 01.01.2016, p. 52-7.

Research output: Contribution to journal › Journal article › Research › peer-review

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abstract = "OBJECTIVE: Cardiovascular implantable electronic device (CIED) infections are increasing in numbers. The objective was to review the clinical presentation and outcome in patients affected with CIED infections with either local pocket or systemic presentation.DESIGN: All device removals due to CIED infection during the period from 2005 to 2012 were retrospectively reviewed. CIED infections were categorized as systemic or pocket infections. Treatment included complete removal of the device, followed by antibiotic treatment of six weeks.RESULTS: Seventy-one device removals due to infection (32 systemic and 39 pocket infections) were recorded during the study period. Median follow-up time was 26 (IQR 9-41) months, 30 day and 12 month mortality were 4% and 14%, respectively. There was no long-term difference in mortality between patients with pocket vs. systemic infection (p = 0.48). During follow-up no relapses and two cases of new infections were noted (2.8%).CONCLUSIONS: CIED infection with systemic or pocket infection was difficult to distinguish in clinical presentation and outcome. Complete device removal and antibiotic treatment of long duration was safe and without relapses.",

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T2 - Complete device removal and long-term antibiotic treatment; long-term outcome

AU - Ihlemann, Nikolaj

AU - Møller-Hansen, Michael

AU - Salado-Rasmussen, Kirsten

AU - Videbæk, Regitze

AU - Moser, Claus

AU - Iversen, Kasper

AU - Bundgaard, Henning

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N2 - OBJECTIVE: Cardiovascular implantable electronic device (CIED) infections are increasing in numbers. The objective was to review the clinical presentation and outcome in patients affected with CIED infections with either local pocket or systemic presentation.DESIGN: All device removals due to CIED infection during the period from 2005 to 2012 were retrospectively reviewed. CIED infections were categorized as systemic or pocket infections. Treatment included complete removal of the device, followed by antibiotic treatment of six weeks.RESULTS: Seventy-one device removals due to infection (32 systemic and 39 pocket infections) were recorded during the study period. Median follow-up time was 26 (IQR 9-41) months, 30 day and 12 month mortality were 4% and 14%, respectively. There was no long-term difference in mortality between patients with pocket vs. systemic infection (p = 0.48). During follow-up no relapses and two cases of new infections were noted (2.8%).CONCLUSIONS: CIED infection with systemic or pocket infection was difficult to distinguish in clinical presentation and outcome. Complete device removal and antibiotic treatment of long duration was safe and without relapses.

AB - OBJECTIVE: Cardiovascular implantable electronic device (CIED) infections are increasing in numbers. The objective was to review the clinical presentation and outcome in patients affected with CIED infections with either local pocket or systemic presentation.DESIGN: All device removals due to CIED infection during the period from 2005 to 2012 were retrospectively reviewed. CIED infections were categorized as systemic or pocket infections. Treatment included complete removal of the device, followed by antibiotic treatment of six weeks.RESULTS: Seventy-one device removals due to infection (32 systemic and 39 pocket infections) were recorded during the study period. Median follow-up time was 26 (IQR 9-41) months, 30 day and 12 month mortality were 4% and 14%, respectively. There was no long-term difference in mortality between patients with pocket vs. systemic infection (p = 0.48). During follow-up no relapses and two cases of new infections were noted (2.8%).CONCLUSIONS: CIED infection with systemic or pocket infection was difficult to distinguish in clinical presentation and outcome. Complete device removal and antibiotic treatment of long duration was safe and without relapses.

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CIED infection with either pocket or systemic infection presentation: Complete device removal and long-term antibiotic treatment; long-term outcome

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