Chronic post-thoracotomy pain - What is new in pathogenic mechanisms and strategies for prevention?

Kim Wildgaard, Henrik Kehlet

    12 Citations (Scopus)

    Abstract

    Recently, the development of persistent postsurgical pain states has received much attention. As a model for understanding persistent postsurgical pain, thoracotomy and its minimal invasive counterpart, video-assisted thoracic surgery, have been investigated. The present article presents recent developments in pathophysiology of post-thoracotomy pain syndrome (PTPS) in regards to pre-, intra-, and postoperative factors. Although the literature is abundant with trials on PTPS, inadequate and inconsistent inclusion of relevant pre-, intra-, and postoperative factors is still problematic. Future trials delineating pain areas and assessing sensory dysfunction support the importance of nerve injury, but other factors are insufficiently investigated. Finally, there is a need for validated detailed procedure-specific questionnaires to assess the function and psychosocial consequences of PTPS.

    Original languageEnglish
    JournalTechniques in Regional Anesthesia and Pain Management
    Volume15
    Issue number3
    Pages (from-to)83 - 89
    Number of pages7
    ISSN1084-208X
    DOIs
    Publication statusPublished - Jul 2011

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