Chronic inflammatory demyelinative polyneuropathy

Gérard Said, Christian Krarup

17 Citations (Scopus)

Abstract

Chronic inflammatory demyelinative polyneuropathy (CIDP) is an acquired polyneuropathy presumably of immunological origin. It is characterized by a progressive or a relapsing course with predominant motor deficit. The diagnosis rests on the association of non-length-dependent predominantly motor deficit following a progressive or a relapsing course associated with increased CSF protein content. The demonstration of asymmetrical demyelinating features on nerve conduction studies is needed for diagnosis. The outcome depends on the amplitude of axon loss associated with demyelination. CIDP must be differentiated from acquired demyelinative neuropathies associated with monoclonal gammopathies. CIDP responds well to treatment with corticosteroids, intravenous immunoglobulins, and plasma exchanges, at least initially.

Original languageEnglish
Title of host publicationHandbook of Clinical Neurology
EditorsMichael Aminoff, Francois Boller, Dick Swaab
Number of pages11
Volume115
PublisherElsevier
Publication date2013
Edition2013
Pages403-413
Chapter22
DOIs
Publication statusPublished - 2013
SeriesHandbook of Clinical Neurology
ISSN0072-9752

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