Characteristics of acute pain attacks in patients with irritable bowel syndrome meeting Rome III criteria

P.M. Hellström, Y.A. Saito, P. Bytzer, J. Tack, S. Mueller-Lissner, L. Chang

    19 Citations (Scopus)

    Abstract

    Objectives: An international multicenter, prospective, non-interventional, 2-month study characterized acute pain attacks in patients with irritable bowel syndrome (IBS). Methods: Adult patients meeting the Rome III IBS diagnostic criteria with a history of 3 pain attacks per month participated in a survey that captured daily and episodic information regarding IBS symptoms and pain attacks for 2 months. Acute pain attacks were defined as a sudden onset or increase in the intensity of IBS abdominal pain with a minimum intensity of 4 (0-10 scale). Results: The majority (84%) of the 158 patients taking the survey were women with a mean age of 41 years and time since IBS diagnosis of 5 years. The median pain attack frequency was 5.4 attacks per month and was significantly higher in the IBS with diarrhea (IBS-D, 6.4 per month) group vs. the IBS with constipation (4.4 per month) and the IBS with mixed pattern (5.5 per month) groups (P
    Original languageEnglish
    JournalAmerican Journal of Gastroenterology
    Volume106
    Issue number7
    Pages (from-to)1299-1307
    Number of pages9
    ISSN0002-9270
    DOIs
    Publication statusPublished - 1 Jul 2011

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