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Challenges in developing drugs for primary headaches
Henrik Winther Schytz
, Richard Hargreaves,
Messoud Ashina
Department of Clinical Medicine
15
Citations (Scopus)
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Keyphrases
Headache
100%
Primary Headache
100%
Drug Development
50%
Nitric Oxide Synthase Inhibition
25%
Subclassification
25%
Triptans
25%
Migraine Pain
25%
Receptor Antagonism
25%
Cortical Spreading Depression
25%
Receptor Agonist
25%
Headache Pain
25%
Sentinel
25%
Antimigraine Drugs
25%
Triage
25%
Drug pipeline
25%
Neurobiology
25%
Near Miss
25%
Pain Models
25%
Substance P
25%
Calcitonin Gene-related Peptide
25%
Human Experimental Models
25%
Glutamate Receptors
25%
Pathophysiology
25%
Serotonin
25%
Drug Discovery
25%
Drug History
25%
Antagonism
25%
Individualized Treatment
25%
Medicine and Dentistry
Headache
100%
Primary Headache
100%
Medicine
28%
Migraine
14%
Nitric Oxide Synthase
14%
Pathophysiology
14%
Biological Marker
14%
Calcitonin Gene Related Peptide
14%
Glutamate Receptor
14%
Receptor
14%
Antimigraine Agent
14%
Cortical Spreading Depression
14%
Triage
14%
Mediator
14%
Side Effect
14%
Serotonin
14%
Substance P
14%
Pharmacology, Toxicology and Pharmaceutical Science
Primary Headache
100%
Headache
100%
Drug Development
28%
Drug Discovery
28%
Pathophysiology
14%
Antimigraine Agent
14%
Receptor Agonist
14%
Calcitonin Gene Related Peptide
14%
Nitric Oxide Synthase
14%
Side Effect
14%
Substance P
14%
Serotonin
14%
Migraine
14%
Biological Marker
14%
Glutamate Receptor
14%
Neuroscience
Headache
100%
Neuroscience
9%
Receptor Agonists
9%
Spreading Cortical Depression
9%
Substance P
9%
Migraine
9%
Antimigraine
9%
Serotonin
9%
Nitric Oxide Synthase
9%
Glutamate Receptor
9%
Calcitonin
9%