Abstract
Does sodium dodecyl sulfate (SDS) denature proteins through electrostatic SDS-protein interactions? We show that a protein completely lacking charged side chains is unfolded by SDS in a manner similar to charged proteins, revealing that formal protein charges are not required for SDS-induced protein unfolding or binding.
Original language | English |
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Journal | Biophysical Journal |
Volume | 115 |
Issue number | 11 |
Pages (from-to) | 2081-2086 |
Number of pages | 6 |
ISSN | 0006-3495 |
DOIs | |
Publication status | Published - 2018 |