Abstract
The natriuretic peptide system comprises three structurally related peptides: atrial natriuretic peptide, B-type natriuretic peptide and C-type natriuretic peptide. In circulation, they play an important endocrine role in the regulation of cardiovascular homeostasis by maintaining blood pressure and extracellular fluid volume. Atrial natriuretic peptide and B-type natriuretic peptide have gained considerable diagnostic interest as biomarkers in cardiovascular disease. By contrast, C-type natriuretic peptide has not yet been ascribed a role in human diagnostics. This perspective aims at recapitulating the present biochemical and clinical issues concerning C-type natriuretic peptide measurement in plasma as a potential biomarker.
| Original language | English |
|---|---|
| Journal | Biomarkers in Medicine |
| Volume | 4 |
| Issue number | 4 |
| Pages (from-to) | 631-9 |
| Number of pages | 9 |
| ISSN | 1752-0363 |
| DOIs | |
| Publication status | Published - 1 Aug 2010 |
