Bystander defibrillation for out-of-hospital cardiac arrest in Public vs Residential Locations

Steen Møller Hansen; Carolina Malta Hansen; Fredrik Folke; Shahzleen Rajan; Kristian Kragholm; Linda Ejlskov; Gunnar Gislason; Lars Køber; Thomas A. Gerds; Søren Hjortshøj; Freddy Lippert; Christian Torp-Pedersen; Mads Wissenberg

doi:10.1001/jamacardio.2017.0008

Bystander defibrillation for out-of-hospital cardiac arrest in Public vs Residential Locations

Steen Møller Hansen^*, Carolina Malta Hansen, Fredrik Folke, Shahzleen Rajan, Kristian Kragholm, Linda Ejlskov, Gunnar Gislason, Lars Køber, Thomas A. Gerds, Søren Hjortshøj, Freddy Lippert, Christian Torp-Pedersen, Mads Wissenberg

^*Corresponding author for this work

56 Citations (Scopus)

Abstract

Importance: Bystander-delivered defibrillation (hereinafter referred to as bystander defibrillation) of patients with out-of-hospital cardiac arrests (OHCAs) remains limited despite the widespread dissemination of automated external defibrillators (AEDs). Objective: To examine calendar changes in bystander defibrillation and subsequent survival according to a public or a residential location of the cardiac arrest after nationwide initiatives in Denmark to facilitate bystander-mediated resuscitative efforts, including bystander defibrillation. Design, Setting, and Participants: This nationwide study identified 18 688 patients in Denmark with first-time OHCA from June 1, 2001, to December 31, 2012, using the Danish Cardiac Arrest Registry. Patients had a presumed cardiac cause of arrest that was not witnessed by emergency medical services personnel. Data were analyzed from April 1, 2015, to December 10, 2016. Exposures: Nationwide initiatives to facilitate bystander resuscitative efforts, including bystander defibrillation, consisted of resuscitation training of Danish citizens, dissemination of on-site AEDs, foundation of an AED registry linked to emergency medical dispatch centers, and dispatcher-assisted guidance of bystander resuscitation efforts. Main Outcomes and Measures: The proportion of patients who received bystander defibrillation according to the location of the cardiac arrest and their subsequent 30-day survival. Results: Of the 18 688 patients with OHCAs (67.8%men and 32.2%women; median [interquartile range] age, 72 [62-80] years), 4783 (25.6%) had a cardiac arrest in a public location and 13 905 (74.4%) in a residential location. The number of registered AEDs increased from 141 in 2007 to 7800 in 2012. The distribution of AED location was consistently skewed in favor of public locations. Bystander defibrillation increased in public locations from 3 of 245 (1.2%; 95%CI, 0.4%-3.5%) in 2001 to 78 of 510 (15.3%; 95%CI, 12.4%-18.7%) in 2012 (P < .001) but remained unchanged in residential locations from 7 of 542 (1.3%; 95%CI, 0.6%-2.6%) in 2001 to 21 of 1669 (1.3%; 95%CI, 0.8%-1.9%) in 2012 (P = .17). Thirty-day survival after bystander defibrillation increased in public locations from 8.3%(95%CI, 1.5%-35.4%) in 2001/2002 to 57.5%(95%CI, 48.6%-66.0%) in 2011/2012 (P < .001) in residential locations, from 0.0%(95%CI, 0.0%-19.4%) in 2001/2002 to 25.6%(95%CI, 14.6%-41.1%) in 2011/2012 (P < .001). Conclusions and Relevance: Initiatives to facilitate bystander defibrillationwere associated with a marked increase in bystander defibrillation in public locations, whereas bystander defibrillation remained limited in residential locations. Concomitantly, survival increased after bystander defibrillation in residential and public locations.

Original language	English
Journal	JAMA Cardiology
Volume	2
Issue number	5
Pages (from-to)	507-514
ISSN	2380-6583
DOIs	https://doi.org/10.1001/jamacardio.2017.0008
Publication status	Published - 2017

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http://europepmc.org/articles/pmc5814985

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@article{a641ee5bf0de459084d3f82337911963,

title = "Bystander defibrillation for out-of-hospital cardiac arrest in Public vs Residential Locations",

abstract = "Importance: Bystander-delivered defibrillation (hereinafter referred to as bystander defibrillation) of patients with out-of-hospital cardiac arrests (OHCAs) remains limited despite the widespread dissemination of automated external defibrillators (AEDs). Objective: To examine calendar changes in bystander defibrillation and subsequent survival according to a public or a residential location of the cardiac arrest after nationwide initiatives in Denmark to facilitate bystander-mediated resuscitative efforts, including bystander defibrillation. Design, Setting, and Participants: This nationwide study identified 18 688 patients in Denmark with first-time OHCA from June 1, 2001, to December 31, 2012, using the Danish Cardiac Arrest Registry. Patients had a presumed cardiac cause of arrest that was not witnessed by emergency medical services personnel. Data were analyzed from April 1, 2015, to December 10, 2016. Exposures: Nationwide initiatives to facilitate bystander resuscitative efforts, including bystander defibrillation, consisted of resuscitation training of Danish citizens, dissemination of on-site AEDs, foundation of an AED registry linked to emergency medical dispatch centers, and dispatcher-assisted guidance of bystander resuscitation efforts. Main Outcomes and Measures: The proportion of patients who received bystander defibrillation according to the location of the cardiac arrest and their subsequent 30-day survival. Results: Of the 18 688 patients with OHCAs (67.8%men and 32.2%women; median [interquartile range] age, 72 [62-80] years), 4783 (25.6%) had a cardiac arrest in a public location and 13 905 (74.4%) in a residential location. The number of registered AEDs increased from 141 in 2007 to 7800 in 2012. The distribution of AED location was consistently skewed in favor of public locations. Bystander defibrillation increased in public locations from 3 of 245 (1.2%; 95%CI, 0.4%-3.5%) in 2001 to 78 of 510 (15.3%; 95%CI, 12.4%-18.7%) in 2012 (P < .001) but remained unchanged in residential locations from 7 of 542 (1.3%; 95%CI, 0.6%-2.6%) in 2001 to 21 of 1669 (1.3%; 95%CI, 0.8%-1.9%) in 2012 (P = .17). Thirty-day survival after bystander defibrillation increased in public locations from 8.3%(95%CI, 1.5%-35.4%) in 2001/2002 to 57.5%(95%CI, 48.6%-66.0%) in 2011/2012 (P < .001) in residential locations, from 0.0%(95%CI, 0.0%-19.4%) in 2001/2002 to 25.6%(95%CI, 14.6%-41.1%) in 2011/2012 (P < .001). Conclusions and Relevance: Initiatives to facilitate bystander defibrillationwere associated with a marked increase in bystander defibrillation in public locations, whereas bystander defibrillation remained limited in residential locations. Concomitantly, survival increased after bystander defibrillation in residential and public locations.",

author = "Hansen, {Steen M{\o}ller} and Hansen, {Carolina Malta} and Fredrik Folke and Shahzleen Rajan and Kristian Kragholm and Linda Ejlskov and Gunnar Gislason and Lars K{\o}ber and Gerds, {Thomas A.} and S{\o}ren Hjortsh{\o}j and Freddy Lippert and Christian Torp-Pedersen and Mads Wissenberg",

year = "2017",

doi = "10.1001/jamacardio.2017.0008",

language = "English",

volume = "2",

pages = "507--514",

journal = "JAMA Cardiology",

issn = "2380-6583",

publisher = "American Medical Association",

number = "5",

}

TY - JOUR

T1 - Bystander defibrillation for out-of-hospital cardiac arrest in Public vs Residential Locations

AU - Hansen, Steen Møller

AU - Hansen, Carolina Malta

AU - Folke, Fredrik

AU - Rajan, Shahzleen

AU - Kragholm, Kristian

AU - Ejlskov, Linda

AU - Gislason, Gunnar

AU - Køber, Lars

AU - Gerds, Thomas A.

AU - Hjortshøj, Søren

AU - Lippert, Freddy

AU - Torp-Pedersen, Christian

AU - Wissenberg, Mads

PY - 2017

Y1 - 2017

N2 - Importance: Bystander-delivered defibrillation (hereinafter referred to as bystander defibrillation) of patients with out-of-hospital cardiac arrests (OHCAs) remains limited despite the widespread dissemination of automated external defibrillators (AEDs). Objective: To examine calendar changes in bystander defibrillation and subsequent survival according to a public or a residential location of the cardiac arrest after nationwide initiatives in Denmark to facilitate bystander-mediated resuscitative efforts, including bystander defibrillation. Design, Setting, and Participants: This nationwide study identified 18 688 patients in Denmark with first-time OHCA from June 1, 2001, to December 31, 2012, using the Danish Cardiac Arrest Registry. Patients had a presumed cardiac cause of arrest that was not witnessed by emergency medical services personnel. Data were analyzed from April 1, 2015, to December 10, 2016. Exposures: Nationwide initiatives to facilitate bystander resuscitative efforts, including bystander defibrillation, consisted of resuscitation training of Danish citizens, dissemination of on-site AEDs, foundation of an AED registry linked to emergency medical dispatch centers, and dispatcher-assisted guidance of bystander resuscitation efforts. Main Outcomes and Measures: The proportion of patients who received bystander defibrillation according to the location of the cardiac arrest and their subsequent 30-day survival. Results: Of the 18 688 patients with OHCAs (67.8%men and 32.2%women; median [interquartile range] age, 72 [62-80] years), 4783 (25.6%) had a cardiac arrest in a public location and 13 905 (74.4%) in a residential location. The number of registered AEDs increased from 141 in 2007 to 7800 in 2012. The distribution of AED location was consistently skewed in favor of public locations. Bystander defibrillation increased in public locations from 3 of 245 (1.2%; 95%CI, 0.4%-3.5%) in 2001 to 78 of 510 (15.3%; 95%CI, 12.4%-18.7%) in 2012 (P < .001) but remained unchanged in residential locations from 7 of 542 (1.3%; 95%CI, 0.6%-2.6%) in 2001 to 21 of 1669 (1.3%; 95%CI, 0.8%-1.9%) in 2012 (P = .17). Thirty-day survival after bystander defibrillation increased in public locations from 8.3%(95%CI, 1.5%-35.4%) in 2001/2002 to 57.5%(95%CI, 48.6%-66.0%) in 2011/2012 (P < .001) in residential locations, from 0.0%(95%CI, 0.0%-19.4%) in 2001/2002 to 25.6%(95%CI, 14.6%-41.1%) in 2011/2012 (P < .001). Conclusions and Relevance: Initiatives to facilitate bystander defibrillationwere associated with a marked increase in bystander defibrillation in public locations, whereas bystander defibrillation remained limited in residential locations. Concomitantly, survival increased after bystander defibrillation in residential and public locations.

AB - Importance: Bystander-delivered defibrillation (hereinafter referred to as bystander defibrillation) of patients with out-of-hospital cardiac arrests (OHCAs) remains limited despite the widespread dissemination of automated external defibrillators (AEDs). Objective: To examine calendar changes in bystander defibrillation and subsequent survival according to a public or a residential location of the cardiac arrest after nationwide initiatives in Denmark to facilitate bystander-mediated resuscitative efforts, including bystander defibrillation. Design, Setting, and Participants: This nationwide study identified 18 688 patients in Denmark with first-time OHCA from June 1, 2001, to December 31, 2012, using the Danish Cardiac Arrest Registry. Patients had a presumed cardiac cause of arrest that was not witnessed by emergency medical services personnel. Data were analyzed from April 1, 2015, to December 10, 2016. Exposures: Nationwide initiatives to facilitate bystander resuscitative efforts, including bystander defibrillation, consisted of resuscitation training of Danish citizens, dissemination of on-site AEDs, foundation of an AED registry linked to emergency medical dispatch centers, and dispatcher-assisted guidance of bystander resuscitation efforts. Main Outcomes and Measures: The proportion of patients who received bystander defibrillation according to the location of the cardiac arrest and their subsequent 30-day survival. Results: Of the 18 688 patients with OHCAs (67.8%men and 32.2%women; median [interquartile range] age, 72 [62-80] years), 4783 (25.6%) had a cardiac arrest in a public location and 13 905 (74.4%) in a residential location. The number of registered AEDs increased from 141 in 2007 to 7800 in 2012. The distribution of AED location was consistently skewed in favor of public locations. Bystander defibrillation increased in public locations from 3 of 245 (1.2%; 95%CI, 0.4%-3.5%) in 2001 to 78 of 510 (15.3%; 95%CI, 12.4%-18.7%) in 2012 (P < .001) but remained unchanged in residential locations from 7 of 542 (1.3%; 95%CI, 0.6%-2.6%) in 2001 to 21 of 1669 (1.3%; 95%CI, 0.8%-1.9%) in 2012 (P = .17). Thirty-day survival after bystander defibrillation increased in public locations from 8.3%(95%CI, 1.5%-35.4%) in 2001/2002 to 57.5%(95%CI, 48.6%-66.0%) in 2011/2012 (P < .001) in residential locations, from 0.0%(95%CI, 0.0%-19.4%) in 2001/2002 to 25.6%(95%CI, 14.6%-41.1%) in 2011/2012 (P < .001). Conclusions and Relevance: Initiatives to facilitate bystander defibrillationwere associated with a marked increase in bystander defibrillation in public locations, whereas bystander defibrillation remained limited in residential locations. Concomitantly, survival increased after bystander defibrillation in residential and public locations.

U2 - 10.1001/jamacardio.2017.0008

DO - 10.1001/jamacardio.2017.0008

M3 - Journal article

C2 - 28297003

AN - SCOPUS:85028611068

SN - 2380-6583

VL - 2

SP - 507

EP - 514

JO - JAMA Cardiology

JF - JAMA Cardiology

IS - 5

ER -

Bystander defibrillation for out-of-hospital cardiac arrest in Public vs Residential Locations

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