Brain malformation in single median maxillary central incisor

TY - JOUR

T1 - Brain malformation in single median maxillary central incisor

AU - Kjaer, I

AU - Wagner, Aa

AU - Thomsen, L L

AU - Holm, K

N1 - Copyright Georg Thieme Verlag KG Stuttgart New York.

PY - 2009/12/1

Y1 - 2009/12/1

N2 - Clinical and radiographic examinations and MR scan of a 12-year-old girl with SMMCI (single median maxillary central incisor) showed impaired growth and a midline defect involving the central incisor, cranium and the midline structures in the brain, falx cerebri and pituitary gland. She had a severe growth hormone deficiency but no other pituitary hormone deficiencies. She was treated with growth hormone and followed during a four-year period with successful gain in body height and sexual maturation. This study focuses on the developmental association between the involved structures and provides guidelines for early diagnostics.

AB - Clinical and radiographic examinations and MR scan of a 12-year-old girl with SMMCI (single median maxillary central incisor) showed impaired growth and a midline defect involving the central incisor, cranium and the midline structures in the brain, falx cerebri and pituitary gland. She had a severe growth hormone deficiency but no other pituitary hormone deficiencies. She was treated with growth hormone and followed during a four-year period with successful gain in body height and sexual maturation. This study focuses on the developmental association between the involved structures and provides guidelines for early diagnostics.

KW - Adolescent

KW - Female

KW - Humans

KW - Jaw Abnormalities

KW - Magnetic Resonance Imaging

KW - Nervous System Malformations

KW - Radiography, Panoramic

KW - Tooth Abnormalities

U2 - 10.1055/s-0030-1248245

DO - 10.1055/s-0030-1248245

M3 - Journal article

C2 - 20446222

SN - 0174-304X

VL - 40

SP - 280

EP - 283

JO - Neuropediatrics

JF - Neuropediatrics

IS - 6

ER -