Bone mineral density in lifelong trained male football players compared with young and elderly untrained men

Marie Hagman; Eva Wulff Helge; Therese Hornstrup; Bjørn Fristrup; Jens Jung Nielsen; Niklas Rye Jørgensen; Jesper Løvind Andersen; Jørn Wulff Helge; Peter Krustrup

doi:10.1016/j.jshs.2017.09.009

Bone mineral density in lifelong trained male football players compared with young and elderly untrained men

Marie Hagman, Eva Wulff Helge, Therese Hornstrup, Bjørn Fristrup, Jens Jung Nielsen, Niklas Rye Jørgensen, Jesper Løvind Andersen, Jørn Wulff Helge, Peter Krustrup^*

^*Corresponding author for this work

17 Citations (Scopus)

70 Downloads (Pure)

Abstract

Purpose: The purpose of the present controlled cross-sectional study was to investigate proximal femur and whole-body bone mineral density (BMD), as well as bone turnover profile, in lifelong trained elderly male football players and young elite football players compared with untrained age-matched men.

Methods: One hundred and forty healthy, non-smoking men participated in the study, including lifelong trained football players (FTE, n = 35) aged 65-80 years, elite football players (FTY, n = 35) aged 18-30 years, as well as untrained age-matched elderly (UE, n = 35) and young (UY, n = 35) men. All participants underwent a regional Dual-Energy X-ray Absorptiometry (DXA) scan of the proximal femur and a whole-body DXA scan to determine BMD. From a resting blood sample, the bone turnover markers (BTMs) osteocalcin, carboxy-terminal type-1 collagen crosslinks (CTX-1), procollagen type-1 amino-terminal propeptide (P1NP), and sclerostin were measured.

Results: FTE had 7.3%-12.9% higher (p <. 0.05) BMD of the femoral neck, wards, shaft, and total proximal femur in both legs compared to UE, and 9.3%-9.7% higher (p <. 0.05) BMD in femoral trochanter in both legs compared to UY. FTY had 24.3%-37.4% higher (p <. 0.001) BMD in all femoral regions and total proximal femur in both legs compared to UY. The whole-body DXA scan confirmed these results, with FTE showing similar whole-body BMD and 7.9% higher (p <. 0.05) leg BMD compared to UY, and with FTY having 9.6% higher (p <. 0.001) whole-body BMD and 18.2% higher (p <. 0.001) leg BMD compared to UY. The plasma concentration of osteocalcin, CTX-1, and P1NP were 29%, 53%, and 52% higher (p <. 0.01), respectively, in FTY compared to UY.

Conclusion: BMD of the proximal femur and whole-body BMD are markedly higher in lifelong trained male football players aged 65-80 years and young elite football players aged 18-30 years compared to age-matched untrained men. Elderly football players even show higher BMD in femoral trochanter and leg BMD than untrained young despite an age difference of 47 years.

Original language	English
Journal	Journal of Sport and Health Science
Volume	7
Issue number	2
Pages (from-to)	159-168
Number of pages	10
ISSN	2095-2546
DOIs	https://doi.org/10.1016/j.jshs.2017.09.009
Publication status	Published - Apr 2018

Keywords

Bone mass
Bone turnover markers
Dual-Energy X-ray Absorptiometry
Proximal femur bone mineral density
Soccer
Whole-body bone mineral density

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Cite this

@article{9ac6c4923d634005998fc12600d681ea,

title = "Bone mineral density in lifelong trained male football players compared with young and elderly untrained men",

abstract = "Purpose: The purpose of the present controlled cross-sectional study was to investigate proximal femur and whole-body bone mineral density (BMD), as well as bone turnover profile, in lifelong trained elderly male football players and young elite football players compared with untrained age-matched men.Methods: One hundred and forty healthy, non-smoking men participated in the study, including lifelong trained football players (FTE, n = 35) aged 65-80 years, elite football players (FTY, n = 35) aged 18-30 years, as well as untrained age-matched elderly (UE, n = 35) and young (UY, n = 35) men. All participants underwent a regional Dual-Energy X-ray Absorptiometry (DXA) scan of the proximal femur and a whole-body DXA scan to determine BMD. From a resting blood sample, the bone turnover markers (BTMs) osteocalcin, carboxy-terminal type-1 collagen crosslinks (CTX-1), procollagen type-1 amino-terminal propeptide (P1NP), and sclerostin were measured. Results: FTE had 7.3%-12.9% higher (p <. 0.05) BMD of the femoral neck, wards, shaft, and total proximal femur in both legs compared to UE, and 9.3%-9.7% higher (p <. 0.05) BMD in femoral trochanter in both legs compared to UY. FTY had 24.3%-37.4% higher (p <. 0.001) BMD in all femoral regions and total proximal femur in both legs compared to UY. The whole-body DXA scan confirmed these results, with FTE showing similar whole-body BMD and 7.9% higher (p <. 0.05) leg BMD compared to UY, and with FTY having 9.6% higher (p <. 0.001) whole-body BMD and 18.2% higher (p <. 0.001) leg BMD compared to UY. The plasma concentration of osteocalcin, CTX-1, and P1NP were 29%, 53%, and 52% higher (p <. 0.01), respectively, in FTY compared to UY. Conclusion: BMD of the proximal femur and whole-body BMD are markedly higher in lifelong trained male football players aged 65-80 years and young elite football players aged 18-30 years compared to age-matched untrained men. Elderly football players even show higher BMD in femoral trochanter and leg BMD than untrained young despite an age difference of 47 years.",

keywords = "Bone mass, Bone turnover markers, Dual-Energy X-ray Absorptiometry, Proximal femur bone mineral density, Soccer, Whole-body bone mineral density",

author = "Marie Hagman and Helge, {Eva Wulff} and Therese Hornstrup and Bj{\o}rn Fristrup and Nielsen, {Jens Jung} and J{\o}rgensen, {Niklas Rye} and Andersen, {Jesper L{\o}vind} and Helge, {J{\o}rn Wulff} and Peter Krustrup",

note = "CURIS 2018 NEXS 165",

year = "2018",

month = apr,

doi = "10.1016/j.jshs.2017.09.009",

language = "English",

volume = "7",

pages = "159--168",

journal = "Journal of Sport and Health Science",

issn = "2095-2546",

publisher = "Elsevier",

number = "2",

}

TY - JOUR

T1 - Bone mineral density in lifelong trained male football players compared with young and elderly untrained men

AU - Hagman, Marie

AU - Helge, Eva Wulff

AU - Hornstrup, Therese

AU - Fristrup, Bjørn

AU - Nielsen, Jens Jung

AU - Jørgensen, Niklas Rye

AU - Andersen, Jesper Løvind

AU - Helge, Jørn Wulff

AU - Krustrup, Peter

N1 - CURIS 2018 NEXS 165

PY - 2018/4

Y1 - 2018/4

N2 - Purpose: The purpose of the present controlled cross-sectional study was to investigate proximal femur and whole-body bone mineral density (BMD), as well as bone turnover profile, in lifelong trained elderly male football players and young elite football players compared with untrained age-matched men.Methods: One hundred and forty healthy, non-smoking men participated in the study, including lifelong trained football players (FTE, n = 35) aged 65-80 years, elite football players (FTY, n = 35) aged 18-30 years, as well as untrained age-matched elderly (UE, n = 35) and young (UY, n = 35) men. All participants underwent a regional Dual-Energy X-ray Absorptiometry (DXA) scan of the proximal femur and a whole-body DXA scan to determine BMD. From a resting blood sample, the bone turnover markers (BTMs) osteocalcin, carboxy-terminal type-1 collagen crosslinks (CTX-1), procollagen type-1 amino-terminal propeptide (P1NP), and sclerostin were measured. Results: FTE had 7.3%-12.9% higher (p <. 0.05) BMD of the femoral neck, wards, shaft, and total proximal femur in both legs compared to UE, and 9.3%-9.7% higher (p <. 0.05) BMD in femoral trochanter in both legs compared to UY. FTY had 24.3%-37.4% higher (p <. 0.001) BMD in all femoral regions and total proximal femur in both legs compared to UY. The whole-body DXA scan confirmed these results, with FTE showing similar whole-body BMD and 7.9% higher (p <. 0.05) leg BMD compared to UY, and with FTY having 9.6% higher (p <. 0.001) whole-body BMD and 18.2% higher (p <. 0.001) leg BMD compared to UY. The plasma concentration of osteocalcin, CTX-1, and P1NP were 29%, 53%, and 52% higher (p <. 0.01), respectively, in FTY compared to UY. Conclusion: BMD of the proximal femur and whole-body BMD are markedly higher in lifelong trained male football players aged 65-80 years and young elite football players aged 18-30 years compared to age-matched untrained men. Elderly football players even show higher BMD in femoral trochanter and leg BMD than untrained young despite an age difference of 47 years.

AB - Purpose: The purpose of the present controlled cross-sectional study was to investigate proximal femur and whole-body bone mineral density (BMD), as well as bone turnover profile, in lifelong trained elderly male football players and young elite football players compared with untrained age-matched men.Methods: One hundred and forty healthy, non-smoking men participated in the study, including lifelong trained football players (FTE, n = 35) aged 65-80 years, elite football players (FTY, n = 35) aged 18-30 years, as well as untrained age-matched elderly (UE, n = 35) and young (UY, n = 35) men. All participants underwent a regional Dual-Energy X-ray Absorptiometry (DXA) scan of the proximal femur and a whole-body DXA scan to determine BMD. From a resting blood sample, the bone turnover markers (BTMs) osteocalcin, carboxy-terminal type-1 collagen crosslinks (CTX-1), procollagen type-1 amino-terminal propeptide (P1NP), and sclerostin were measured. Results: FTE had 7.3%-12.9% higher (p <. 0.05) BMD of the femoral neck, wards, shaft, and total proximal femur in both legs compared to UE, and 9.3%-9.7% higher (p <. 0.05) BMD in femoral trochanter in both legs compared to UY. FTY had 24.3%-37.4% higher (p <. 0.001) BMD in all femoral regions and total proximal femur in both legs compared to UY. The whole-body DXA scan confirmed these results, with FTE showing similar whole-body BMD and 7.9% higher (p <. 0.05) leg BMD compared to UY, and with FTY having 9.6% higher (p <. 0.001) whole-body BMD and 18.2% higher (p <. 0.001) leg BMD compared to UY. The plasma concentration of osteocalcin, CTX-1, and P1NP were 29%, 53%, and 52% higher (p <. 0.01), respectively, in FTY compared to UY. Conclusion: BMD of the proximal femur and whole-body BMD are markedly higher in lifelong trained male football players aged 65-80 years and young elite football players aged 18-30 years compared to age-matched untrained men. Elderly football players even show higher BMD in femoral trochanter and leg BMD than untrained young despite an age difference of 47 years.

KW - Bone mass

KW - Bone turnover markers

KW - Dual-Energy X-ray Absorptiometry

KW - Proximal femur bone mineral density

KW - Soccer

KW - Whole-body bone mineral density

U2 - 10.1016/j.jshs.2017.09.009

DO - 10.1016/j.jshs.2017.09.009

M3 - Journal article

C2 - 30356456

AN - SCOPUS:85038405800

SN - 2095-2546

VL - 7

SP - 159

EP - 168

JO - Journal of Sport and Health Science

JF - Journal of Sport and Health Science

IS - 2

ER -

Bone mineral density in lifelong trained male football players compared with young and elderly untrained men

Abstract

Keywords

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