Bone mass development in childhood and its association with physical activity and vitamin D levels. The CHAMPS-Study DK

TY - JOUR

T1 - Bone mass development in childhood and its association with physical activity and vitamin D levels. The CHAMPS-Study DK

AU - Rønne, Maria Sode

AU - Heidemann, Malene

AU - Lylloff, Louise

AU - Schou, Anders J

AU - Tarp, Jakob

AU - Laursen, Jens Ole

AU - Jørgensen, Niklas Rye

AU - Husby, Steffen

AU - Wedderkopp, Niels

AU - Mølgaard, Christian

N1 - CURIS 2019 NEXS 024

PY - 2019/1/15

Y1 - 2019/1/15

N2 - This longitudinal study examined associations of bone mass with physical activity and vitamin D level over more than 6 years through puberty. A total of 663 participants (320 boys) with mean age 9.6 years at baseline (10–17 years at follow-up), underwent dual energy X-ray absorptiometry, anthropometry and blood samples for vitamin D at least twice during the study period (with three possible time-points). Physical activity was assessed using accelerometers at follow-up. A positive association was found between percent time spent at vigorous physical activity and total-body less head bone mineral content (β = 5.8, p = 0.002). The magnitude of this association increased with maturational development; thus physical activity may have a greater influence on bone mass in the more mature participants. The vitamin D levels were also positively associated with bone mass. A high degree of tracking was observed with changes in anthropometric Z scores predictive of deviation from tracking. No environmental factor predicted deviation from tracking.

AB - This longitudinal study examined associations of bone mass with physical activity and vitamin D level over more than 6 years through puberty. A total of 663 participants (320 boys) with mean age 9.6 years at baseline (10–17 years at follow-up), underwent dual energy X-ray absorptiometry, anthropometry and blood samples for vitamin D at least twice during the study period (with three possible time-points). Physical activity was assessed using accelerometers at follow-up. A positive association was found between percent time spent at vigorous physical activity and total-body less head bone mineral content (β = 5.8, p = 0.002). The magnitude of this association increased with maturational development; thus physical activity may have a greater influence on bone mass in the more mature participants. The vitamin D levels were also positively associated with bone mass. A high degree of tracking was observed with changes in anthropometric Z scores predictive of deviation from tracking. No environmental factor predicted deviation from tracking.

KW - Bone mass

KW - Dual energy X-ray absorptiometry

KW - Physical activity

KW - Puberty

KW - Tracking

KW - Vitamin D

U2 - 10.1007/s00223-018-0466-5

DO - 10.1007/s00223-018-0466-5

M3 - Journal article

C2 - 30178125

AN - SCOPUS:85052948950

SN - 0171-967X

VL - 104

SP - 1

EP - 13

JO - Calcified Tissue International

JF - Calcified Tissue International

IS - 1

ER -