Bone marrow derived mesenchymal cell mobilization by granulocyte-colony stimulating factor after acute myocardial infarction: results from the Stem Cells in Myocardial Infarction (STEMMI) trial

Rasmus Sejersten Ripa; Mandana Haack-Sørensen; Yongzhong Wang; Erik Jørgensen; Steen Mortensen; Lene Bindslev; Tina Friis; Jens Kastrup

doi:10.1161/CIRCULATIONAHA.106.678649

Bone marrow derived mesenchymal cell mobilization by granulocyte-colony stimulating factor after acute myocardial infarction: results from the Stem Cells in Myocardial Infarction (STEMMI) trial

Rasmus Sejersten Ripa, Mandana Haack-Sørensen, Yongzhong Wang, Erik Jørgensen, Steen Mortensen, Lene Bindslev, Tina Friis, Jens Kastrup

116 Citations (Scopus)

Abstract

Granulocyte-colony stimulating factor (G-CSF) after myocardial infarction does not affect systolic function when compared with placebo. In contrast, intracoronary infusion of bone marrow cells appears to improve ejection fraction. We aimed to evaluate the G-CSF mobilization of subsets of stem cells.

Original language	English
Journal	Circulation
Volume	116
Issue number	11 Suppl
Pages (from-to)	I24-30
ISSN	0009-7322
DOIs	https://doi.org/10.1161/CIRCULATIONAHA.106.678649
Publication status	Published - 11 Sept 2007
Externally published	Yes

Keywords

Aged
Antigens, CD34
Bone Marrow Cells
Double-Blind Method
Female
Granulocyte Colony-Stimulating Factor
Hematopoietic Stem Cell Mobilization
Humans
Male
Mesenchymal Stem Cell Transplantation
Mesenchymal Stromal Cells
Middle Aged
Myocardial Infarction
Ventricular Function, Left

Access to Document

10.1161/CIRCULATIONAHA.106.678649

Cite this

Ripa, R. S., Haack-Sørensen, M., Wang, Y., Jørgensen, E., Mortensen, S., Bindslev, L., Friis, T., & Kastrup, J. (2007). Bone marrow derived mesenchymal cell mobilization by granulocyte-colony stimulating factor after acute myocardial infarction: results from the Stem Cells in Myocardial Infarction (STEMMI) trial. Circulation, 116(11 Suppl), I24-30. https://doi.org/10.1161/CIRCULATIONAHA.106.678649

Bone marrow derived mesenchymal cell mobilization by granulocyte-colony stimulating factor after acute myocardial infarction: results from the Stem Cells in Myocardial Infarction (STEMMI) trial. / Ripa, Rasmus Sejersten; Haack-Sørensen, Mandana; Wang, Yongzhong et al.
In: Circulation, Vol. 116, No. 11 Suppl, 11.09.2007, p. I24-30.

Research output: Contribution to journal › Journal article › Research › peer-review

Ripa, RS, Haack-Sørensen, M, Wang, Y, Jørgensen, E, Mortensen, S, Bindslev, L, Friis, T & Kastrup, J 2007, 'Bone marrow derived mesenchymal cell mobilization by granulocyte-colony stimulating factor after acute myocardial infarction: results from the Stem Cells in Myocardial Infarction (STEMMI) trial', Circulation, vol. 116, no. 11 Suppl, pp. I24-30. https://doi.org/10.1161/CIRCULATIONAHA.106.678649

@article{f3f9841cf9ba479ea548970c7e07ff82,

title = "Bone marrow derived mesenchymal cell mobilization by granulocyte-colony stimulating factor after acute myocardial infarction: results from the Stem Cells in Myocardial Infarction (STEMMI) trial",

abstract = "Granulocyte-colony stimulating factor (G-CSF) after myocardial infarction does not affect systolic function when compared with placebo. In contrast, intracoronary infusion of bone marrow cells appears to improve ejection fraction. We aimed to evaluate the G-CSF mobilization of subsets of stem cells.",

keywords = "Aged, Antigens, CD34, Bone Marrow Cells, Double-Blind Method, Female, Granulocyte Colony-Stimulating Factor, Hematopoietic Stem Cell Mobilization, Humans, Male, Mesenchymal Stem Cell Transplantation, Mesenchymal Stromal Cells, Middle Aged, Myocardial Infarction, Ventricular Function, Left",

author = "Ripa, {Rasmus Sejersten} and Mandana Haack-S{\o}rensen and Yongzhong Wang and Erik J{\o}rgensen and Steen Mortensen and Lene Bindslev and Tina Friis and Jens Kastrup",

year = "2007",

month = sep,

day = "11",

doi = "10.1161/CIRCULATIONAHA.106.678649",

language = "English",

volume = "116",

pages = "I24--30",

journal = "Circulation",

issn = "0009-7322",

publisher = "AHA/ASA",

number = "11 Suppl",

}

TY - JOUR

T1 - Bone marrow derived mesenchymal cell mobilization by granulocyte-colony stimulating factor after acute myocardial infarction

T2 - results from the Stem Cells in Myocardial Infarction (STEMMI) trial

AU - Ripa, Rasmus Sejersten

AU - Haack-Sørensen, Mandana

AU - Wang, Yongzhong

AU - Jørgensen, Erik

AU - Mortensen, Steen

AU - Bindslev, Lene

AU - Friis, Tina

AU - Kastrup, Jens

PY - 2007/9/11

Y1 - 2007/9/11

N2 - Granulocyte-colony stimulating factor (G-CSF) after myocardial infarction does not affect systolic function when compared with placebo. In contrast, intracoronary infusion of bone marrow cells appears to improve ejection fraction. We aimed to evaluate the G-CSF mobilization of subsets of stem cells.

AB - Granulocyte-colony stimulating factor (G-CSF) after myocardial infarction does not affect systolic function when compared with placebo. In contrast, intracoronary infusion of bone marrow cells appears to improve ejection fraction. We aimed to evaluate the G-CSF mobilization of subsets of stem cells.

KW - Aged

KW - Antigens, CD34

KW - Bone Marrow Cells

KW - Double-Blind Method

KW - Female

KW - Granulocyte Colony-Stimulating Factor

KW - Hematopoietic Stem Cell Mobilization

KW - Humans

KW - Male

KW - Mesenchymal Stem Cell Transplantation

KW - Mesenchymal Stromal Cells

KW - Middle Aged

KW - Myocardial Infarction

KW - Ventricular Function, Left

U2 - 10.1161/CIRCULATIONAHA.106.678649

DO - 10.1161/CIRCULATIONAHA.106.678649

M3 - Journal article

C2 - 17846310

SN - 0009-7322

VL - 116

SP - I24-30

JO - Circulation

JF - Circulation

IS - 11 Suppl

ER -

Bone marrow derived mesenchymal cell mobilization by granulocyte-colony stimulating factor after acute myocardial infarction: results from the Stem Cells in Myocardial Infarction (STEMMI) trial

Abstract

Keywords

Access to Document

Fingerprint

Cite this