Bombesin-like immunoreactivity in the nervous system of hydra

TY - JOUR

T1 - Bombesin-like immunoreactivity in the nervous system of hydra

AU - Grimmelikhuijzen, C J

AU - Dockray, G J

AU - Yanaihara, N

PY - 1981/1/1

Y1 - 1981/1/1

N2 - With immunocytochemical methods, nerve cells have been detected in Hydra attenuata containing bombesin-like immunoreactivity. These nerve cells are located in ectoderm of all body regions of the animal and are especially abundant in basal disk and tentacles. Radioimmunoassay of extracts of hydra demonstrated at least 0.2 pmol/g wet weight of bombesin-like immunoreactivity. The immunoreactive material elutes from Sephadex G-50 in a similar position to synthetic bombesin. The data show that bombesin-like peptides are among the phylogenetically oldest neuropeptides found so far.

AB - With immunocytochemical methods, nerve cells have been detected in Hydra attenuata containing bombesin-like immunoreactivity. These nerve cells are located in ectoderm of all body regions of the animal and are especially abundant in basal disk and tentacles. Radioimmunoassay of extracts of hydra demonstrated at least 0.2 pmol/g wet weight of bombesin-like immunoreactivity. The immunoreactive material elutes from Sephadex G-50 in a similar position to synthetic bombesin. The data show that bombesin-like peptides are among the phylogenetically oldest neuropeptides found so far.

KW - Animals

KW - Bombesin

KW - Hydra

KW - Nervous System

KW - Neurons

KW - Peptides

KW - Radioimmunoassay

M3 - Journal article

C2 - 7327945

SN - 0301-5564

VL - 73

SP - 171

EP - 180

JO - Histochemistry

JF - Histochemistry

IS - 2

ER -