Abstract
The individual functional unit of the kidney (the nephron) displays oscillations in its pressure and flow regulation at two different time scales: fast oscillations associated with a myogenic dynamics of the afferent arteriole, and slower oscillations arising from a delay in the tubuloglomerular feedback. We investigate the intra- and internephron entrainment of the two time scales. In addition to full synchronization, both wavelet analyses of experimental data and numerical simulations reveal a partial entrainment in which neighboring nephrons attain a state of chaotic synchronization with respect to their slow dynamics, but the fast dynamics remain desynchronized.
| Original language | English |
|---|---|
| Journal | Physical Review E (Statistical, Nonlinear, and Soft Matter Physics) |
| Volume | 66 |
| Issue number | 6 Pt 1 |
| Pages (from-to) | 061909 |
| ISSN | 1539-3755 |
| Publication status | Published - 2002 |