TY - JOUR
T1 - Behandlingseffekten på reumatoid artritis for de tre eksisterende tumornekrosefaktor-alpha-haemmende behandlinger. Metaanalytisk litteraturstudie--sekundaerpublikation
AU - Christensen, Robin
AU - Kristensen, Lars Erik
AU - Geborek, Pierre
AU - Danneskiold-Samsøe, Bente
AU - Saxne, Tore
AU - Bliddal, Henning
AU - Christensen, Robin
AU - Kristensen, Lars Erik
AU - Geborek, Pierre
AU - Danneskiold-Samsøe, Bente
AU - Saxne, Tore
AU - Bliddal, Henning
N1 - Keywords: Antibodies, Monoclonal; Antirheumatic Agents; Arthritis, Rheumatoid; Humans; Immunoglobulin G; Receptors, Tumor Necrosis Factor; Treatment Outcome
PY - 2009
Y1 - 2009
N2 - Absolute treatment efficacy (via number needed to treat) of rheumatoid arthritis for each of the three available anti tumour necrosis factor alpha inhibiting therapies. Our aim was to indirectly compare the long-term efficacy of the available anti-tumour necrosis factor (TNF) therapies in patients with established rheumatoid arthritis. The results indicate that the absolute efficacy associated with use of these anti-TNF therapies is equivalent if applied in equivalent dosages. In standard dosages, infliximab (3 mg/kg/eight weeks) is only half as effective as adalimumab (40 mg/two weeks) and etanercept (25 mg twice weekly).
Udgivelsesdato: 2009-Jun
AB - Absolute treatment efficacy (via number needed to treat) of rheumatoid arthritis for each of the three available anti tumour necrosis factor alpha inhibiting therapies. Our aim was to indirectly compare the long-term efficacy of the available anti-tumour necrosis factor (TNF) therapies in patients with established rheumatoid arthritis. The results indicate that the absolute efficacy associated with use of these anti-TNF therapies is equivalent if applied in equivalent dosages. In standard dosages, infliximab (3 mg/kg/eight weeks) is only half as effective as adalimumab (40 mg/two weeks) and etanercept (25 mg twice weekly).
Udgivelsesdato: 2009-Jun
M3 - Tidsskriftartikel
SN - 0041-5782
VL - 171
SP - 2192
EP - 2194
JO - Ugeskrift for Laeger
JF - Ugeskrift for Laeger
IS - 26
ER -