B-lymfocytdepletring og andre biologiske behandlingsmuligheder ved Graves' oftalmopatiTumor necrosis factor-alpha binding capacity and anti-infliximab antibodies measured by fluid-phase radioimmunoassays as predictors of clinical efficacy of infliximab in Crohn's disease

Fassi D. El, L. Hegedus, Claus Henrik Nielsen

    1 Citation (Scopus)

    Abstract

    The current medical treatment options for Graves' ophthalmopathy (GO) are unsatisfactory. Recent treatment of GO patients with the B-lymphocyte depleting monoclonal antibody rituximab or with the anti-tumor necrosis factor-alpha agents etanercept and infliximab has shown promising results. We discuss the use of these and other biological agents targeting B lymphocytes, T-lymphocyte interaction with antigen-presenting cells, or cytokines in the future treatment of GO
    Udgivelsesdato: 2008/6/9
    Original languageDanish
    JournalUgeskrift for læger
    Volume170
    Issue number24
    Pages (from-to)2128-2130
    Number of pages2
    ISSN0041-5782
    Publication statusPublished - 2008

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