Automatic J-point Location in Subjects with Electrocardiographic Early Repolarization

TY - JOUR

T1 - Automatic J-point Location in Subjects with Electrocardiographic Early Repolarization

AU - Melgaard, Jacob

AU - Struijk, Johannes J.

AU - Hansen, John

AU - Kanters, Jørgen K.

AU - Jensen, Ask Schou

AU - Schmidt, Samuel

AU - Bhuiyan, Tanveer Ahmed

AU - Graff, Claus

PY - 2014

Y1 - 2014

N2 - Early repolarization (ER) in the inferior/lateral leads of 12-lead EeG increases the risk of arrhythmic death. Automatic methods are needed to robustly locate the J-point in ER positive EeGs so large databases with electrocardiographic ER patterns can be analyzed. We developed an algorithm (Std-12) to determine Jpoint location in the 12-lead EeG based on the standard deviation across the 12 leads. The algorithm was compared to J-point locations determined manually by Minnesota coding of 12-lead EeGs with and without ER. Minnesota coded QRS durations were different in the ER+ and ER-groups. In contrast, the Std-12 algorithm measured similar QRS durations in the ER+ and ERgroups, consistent with the Minnesota coded duration of the ER-group. If the later Minnesota coded J-points were used instead of the earlier J-points otherwise recommended by the Minnesota coding scheme, the QRS durations in the ER-and ER+ groups were similar, and agreed with the Std-12 algorithm. The results of this study suggest that J-points should always be set after any notches or slurs, to help determine the correct QRS duration. The developed Std-12 algorithm seems to robustly determine correct QRS durations, regardless of the electrocardiographic presence of ER.

AB - Early repolarization (ER) in the inferior/lateral leads of 12-lead EeG increases the risk of arrhythmic death. Automatic methods are needed to robustly locate the J-point in ER positive EeGs so large databases with electrocardiographic ER patterns can be analyzed. We developed an algorithm (Std-12) to determine Jpoint location in the 12-lead EeG based on the standard deviation across the 12 leads. The algorithm was compared to J-point locations determined manually by Minnesota coding of 12-lead EeGs with and without ER. Minnesota coded QRS durations were different in the ER+ and ER-groups. In contrast, the Std-12 algorithm measured similar QRS durations in the ER+ and ERgroups, consistent with the Minnesota coded duration of the ER-group. If the later Minnesota coded J-points were used instead of the earlier J-points otherwise recommended by the Minnesota coding scheme, the QRS durations in the ER-and ER+ groups were similar, and agreed with the Std-12 algorithm. The results of this study suggest that J-points should always be set after any notches or slurs, to help determine the correct QRS duration. The developed Std-12 algorithm seems to robustly determine correct QRS durations, regardless of the electrocardiographic presence of ER.

M3 - Journal article

SN - 0276-6574

VL - 41

SP - 585

EP - 588

JO - Computing in Cardiology

JF - Computing in Cardiology

ER -