Automatic detection of childhood absence epilepsy seizures: toward a monitoring device

TY - JOUR

T1 - Automatic detection of childhood absence epilepsy seizures

T2 - toward a monitoring device

AU - Duun-Henriksen, Jonas

AU - Madsen, Rasmus

AU - Remvig, Line S

AU - Thomsen, Carsten E

AU - Sorensen, Helge B D

AU - Kjaer, Troels W

N1 - Copyright © 2012 Elsevier Inc. All rights reserved.

PY - 2012/5

Y1 - 2012/5

N2 - Automatic detections of paroxysms in patients with childhood absence epilepsy have been neglected for several years. We acquire reliable detections using only a single-channel brainwave monitor, allowing for unobtrusive monitoring of antiepileptic drug effects. Ultimately we seek to obtain optimal long-term prognoses, balancing antiepileptic effects and side effects. The electroencephalographic appearance of paroxysms in childhood absence epilepsy is fairly homogeneous, making it feasible to develop patient-independent automatic detection. We implemented a state-of-the-art algorithm to investigate the performance of paroxysm detection. Using only a single scalp electroencephalogram channel from 20 patients with a total of 125 paroxysms >2 seconds, 97.2% of paroxysms could be detected with no false detections. This result leads us to recommend further investigations of tiny, one-channel electroencephalogram systems in an ambulatory setting.

AB - Automatic detections of paroxysms in patients with childhood absence epilepsy have been neglected for several years. We acquire reliable detections using only a single-channel brainwave monitor, allowing for unobtrusive monitoring of antiepileptic drug effects. Ultimately we seek to obtain optimal long-term prognoses, balancing antiepileptic effects and side effects. The electroencephalographic appearance of paroxysms in childhood absence epilepsy is fairly homogeneous, making it feasible to develop patient-independent automatic detection. We implemented a state-of-the-art algorithm to investigate the performance of paroxysm detection. Using only a single scalp electroencephalogram channel from 20 patients with a total of 125 paroxysms >2 seconds, 97.2% of paroxysms could be detected with no false detections. This result leads us to recommend further investigations of tiny, one-channel electroencephalogram systems in an ambulatory setting.

U2 - 10.1016/j.pediatrneurol.2012.02.018

DO - 10.1016/j.pediatrneurol.2012.02.018

M3 - Journal article

C2 - 22520349

SN - 0887-8994

VL - 46

SP - 287

EP - 292

JO - Pediatric Neurology

JF - Pediatric Neurology

IS - 5

ER -