Automated quantification and analysis of mandibular asymmetry.

TA Darvann; Nuno Vibe Hermann; P. Larsen; H. Olafsdottir; IV Hansen; H. Hove; L. Christensen; Sven Kreiborg

Abstract

We present an automated method of spatially detailed 3D asymmetry quantification in mandibles extracted from CT and apply it to a population of infants with unilateral coronal synostosis (UCS). An atlas-based method employing non-rigid registration of surfaces is used for determining deformation fields, thereby establishing detailed anatomical point correspondence between subjects as well as between points on the left and right side of the mid-sagittal plane (MSP). Asymmetry is defined in terms of the vector between a point and the corresponding anatomical point on the opposite side of the MSP after mirroring the mandible across the MSP. A principal components analysis of asymmetry characterizes the major types of asymmetry in the population, and successfully separates the asymmetric UCS mandibles from a number of less asymmetric mandibles from a control population.

Original language	English
Publication date	2010
Number of pages	4
Publication status	Published - 2010
Event	IEEE International Symposium on Medical Imaging, Rotterdam 2010. - Rotter, Netherlands Duration: 29 Nov 2010 → …

Conference

Conference	IEEE International Symposium on Medical Imaging, Rotterdam 2010.
Country/Territory	Netherlands
City	Rotter
Period	29/11/2010 → …

Cite this

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title = "Automated quantification and analysis of mandibular asymmetry.",

abstract = "We present an automated method of spatially detailed 3D asymmetry quantification in mandibles extracted from CT and apply it to a population of infants with unilateral coronal synostosis (UCS). An atlas-based method employing non-rigid registration of surfaces is used for determining deformation fields, thereby establishing detailed anatomical point correspondence between subjects as well as between points on the left and right side of the mid-sagittal plane (MSP). Asymmetry is defined in terms of the vector between a point and the corresponding anatomical point on the opposite side of the MSP after mirroring the mandible across the MSP. A principal components analysis of asymmetry characterizes the major types of asymmetry in the population, and successfully separates the asymmetric UCS mandibles from a number of less asymmetric mandibles from a control population.",

author = "TA Darvann and Hermann, {Nuno Vibe} and P. Larsen and H. Olafsdottir and IV Hansen and H. Hove and L. Christensen and Sven Kreiborg",

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TY - ABST

T1 - Automated quantification and analysis of mandibular asymmetry.

AU - Darvann, TA

AU - Hermann, Nuno Vibe

AU - Larsen, P.

AU - Olafsdottir, H.

AU - Hansen, IV

AU - Hove, H.

AU - Christensen, L.

AU - Kreiborg, Sven

N1 - Sider: 416-9

PY - 2010

Y1 - 2010

N2 - We present an automated method of spatially detailed 3D asymmetry quantification in mandibles extracted from CT and apply it to a population of infants with unilateral coronal synostosis (UCS). An atlas-based method employing non-rigid registration of surfaces is used for determining deformation fields, thereby establishing detailed anatomical point correspondence between subjects as well as between points on the left and right side of the mid-sagittal plane (MSP). Asymmetry is defined in terms of the vector between a point and the corresponding anatomical point on the opposite side of the MSP after mirroring the mandible across the MSP. A principal components analysis of asymmetry characterizes the major types of asymmetry in the population, and successfully separates the asymmetric UCS mandibles from a number of less asymmetric mandibles from a control population.

AB - We present an automated method of spatially detailed 3D asymmetry quantification in mandibles extracted from CT and apply it to a population of infants with unilateral coronal synostosis (UCS). An atlas-based method employing non-rigid registration of surfaces is used for determining deformation fields, thereby establishing detailed anatomical point correspondence between subjects as well as between points on the left and right side of the mid-sagittal plane (MSP). Asymmetry is defined in terms of the vector between a point and the corresponding anatomical point on the opposite side of the MSP after mirroring the mandible across the MSP. A principal components analysis of asymmetry characterizes the major types of asymmetry in the population, and successfully separates the asymmetric UCS mandibles from a number of less asymmetric mandibles from a control population.

M3 - Conference abstract for conference

T2 - IEEE International Symposium on Medical Imaging, Rotterdam 2010.

Y2 - 29 November 2010

ER -

Automated quantification and analysis of mandibular asymmetry.

Abstract

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