Atlantinone A, a meroterpenoid produced by Penicillium ribeum and several cheese associated Penicillium species

Petur Weihe Dalsgaard; Bent Petersen; Jens Ø. Duus; Christian Zidorn; Jens Christian Frisvad; Carsten Christophersen; Thomas Ostenfeld Larsen

Atlantinone A, a meroterpenoid produced by Penicillium ribeum and several cheese associated Penicillium species

Petur Weihe Dalsgaard, Bent Petersen, Jens Ø. Duus, Christian Zidorn, Jens Christian Frisvad, Carsten Christophersen, Thomas Ostenfeld Larsen

8 Citations (Scopus)

Abstract

Atlantinone A has been isolated from the psychrotolerant fungus Penicillium ribeum. The exact structure of the compound was confirmed by mass spectrometric and 1- and 2D NMR experiments. Atlantinone A was originally only produced upon chemical epigenetic manipulation of P. hirayamae, however in this study the compound was found to be produced at standard growth conditions by the following species; P. solitum, P. discolor, P. commune, P. caseifulvum, P. palitans, P. novae-zeelandiae and P. monticola. A biosynthetic pathway to atlantinone A starting from andrastin A is proposed.

Original language	English
Journal	Metabolites
Volume	2
Issue number	1
Pages (from-to)	214-220
Number of pages	7
ISSN	2218-1989
Publication status	Published - 23 Feb 2012

Access to Document

http://www.mdpi.com/2218-1989/2/1/214

Cite this

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title = "Atlantinone A, a meroterpenoid produced by Penicillium ribeum and several cheese associated Penicillium species",

abstract = "Atlantinone A has been isolated from the psychrotolerant fungus Penicillium ribeum. The exact structure of the compound was confirmed by mass spectrometric and 1- and 2D NMR experiments. Atlantinone A was originally only produced upon chemical epigenetic manipulation of P. hirayamae, however in this study the compound was found to be produced at standard growth conditions by the following species; P. solitum, P. discolor, P. commune, P. caseifulvum, P. palitans, P. novae-zeelandiae and P. monticola. A biosynthetic pathway to atlantinone A starting from andrastin A is proposed.",

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author = "Dalsgaard, {Petur Weihe} and Bent Petersen and Duus, {Jens {\O}.} and Christian Zidorn and Frisvad, {Jens Christian} and Carsten Christophersen and Larsen, {Thomas Ostenfeld}",

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T1 - Atlantinone A, a meroterpenoid produced by Penicillium ribeum and several cheese associated Penicillium species

AU - Dalsgaard, Petur Weihe

AU - Petersen, Bent

AU - Duus, Jens Ø.

AU - Zidorn, Christian

AU - Frisvad, Jens Christian

AU - Christophersen, Carsten

AU - Larsen, Thomas Ostenfeld

PY - 2012/2/23

Y1 - 2012/2/23

N2 - Atlantinone A has been isolated from the psychrotolerant fungus Penicillium ribeum. The exact structure of the compound was confirmed by mass spectrometric and 1- and 2D NMR experiments. Atlantinone A was originally only produced upon chemical epigenetic manipulation of P. hirayamae, however in this study the compound was found to be produced at standard growth conditions by the following species; P. solitum, P. discolor, P. commune, P. caseifulvum, P. palitans, P. novae-zeelandiae and P. monticola. A biosynthetic pathway to atlantinone A starting from andrastin A is proposed.

AB - Atlantinone A has been isolated from the psychrotolerant fungus Penicillium ribeum. The exact structure of the compound was confirmed by mass spectrometric and 1- and 2D NMR experiments. Atlantinone A was originally only produced upon chemical epigenetic manipulation of P. hirayamae, however in this study the compound was found to be produced at standard growth conditions by the following species; P. solitum, P. discolor, P. commune, P. caseifulvum, P. palitans, P. novae-zeelandiae and P. monticola. A biosynthetic pathway to atlantinone A starting from andrastin A is proposed.

KW - biology

M3 - Journal article

SN - 2218-1989

VL - 2

SP - 214

EP - 220

JO - Metabolites

JF - Metabolites

IS - 1

ER -