Abstract
Aim: To study the relationships between 25-hydroxyvitamin D status and blood lipids, insulin, glucose, body mass index and waist circumference in infants. Methods: In a cross-sectional study, 255 infants aged 9 months with a blood sample for 25-hydroxyvitamin D were examined. Plasma 25-hydroxyvitamin D concentrations were analysed by chemiluminescent immunoassay. Associations between plasma 25-hydroxyvitamin D and high-density lipoprotein (HDL), low-density lipoprotein, total cholesterol, triglycerides, insulin, glucose, body mass index and waist circumference were analysed. Results: Mean plasma 25-hydroxyvitamin D was 77.2 ± 22.7 nM. At the time of examination, 97% received vitamin D supplementation. 25-Hydroxyvitamin D was negatively associated with HDL (p = 0.003), cholesterol (p = 0.002) and triglycerides (p = 0.010) in multivariate analysis controlled for gender, season, body mass index, length, birth weight and breastfeeding. There were no associations between 25-hydroxyvitamin D and glucose or insulin (all p > 0.05). 25-hydroxyvitamin D was negatively associated with body mass index (p = 0.005) and waist circumference (p = 0.002) controlled for gender, season, breastfeeding, birth weight and length. Conclusion: Vitamin D status is negatively associated with blood lipids, body mass index and waist circumference in infants where nearly all received vitamin D supplements. Whether this has long-term health effects remains to be elucidated.
| Original language | English |
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| Title of host publication | 44th Annual Meeting of the European Society for Pediatric Gastroenterology, Hepatology and Nutrition : Programme and abstract booklet |
| Number of pages | 1 |
| Publication date | Sept 2011 |
| Pages | 255 |
| Publication status | Published - Sept 2011 |
| Event | ESPGHAN - Sorrento, Italy Duration: 25 May 2011 → 28 May 2011 |
Conference
| Conference | ESPGHAN |
|---|---|
| Country/Territory | Italy |
| City | Sorrento |
| Period | 25/05/2011 → 28/05/2011 |