Association between neuromedin U gene variants and overweight and obesity

Irena Hainerová; Signe S Torekov; Jakob Ek; Marie Finková; Knut Borch-Johnsen; Torben Jørgensen; Ole D Madsen; Jan Lebl; Torben Hansen; Oluf Pedersen

doi:10.1210/jc.2006-1442

Association between neuromedin U gene variants and overweight and obesity

Irena Hainerová, Signe S Torekov, Jakob Ek, Marie Finková, Knut Borch-Johnsen, Torben Jørgensen, Ole D Madsen, Jan Lebl, Torben Hansen, Oluf Pedersen

50 Citations (Scopus)

Abstract

Neuromedin U (NMU) is an anorexic neuropeptide expressed in the hypothalamus. Mice lacking the NmU gene are hyperphagic and obese, whereas mice overexpressing Nmu are hypophagic and lean.

Original language	English
Journal	Journal of Clinical Endocrinology and Metabolism
Volume	91
Issue number	12
Pages (from-to)	5057-63
Number of pages	7
ISSN	0021-972X
DOIs	https://doi.org/10.1210/jc.2006-1442
Publication status	Published - 2006

Keywords

Adolescent
Adult
Aged
Amino Acid Sequence
Body Mass Index
Child
Child, Preschool
Female
Genetic Variation
Humans
Infant
Male
Middle Aged
Molecular Sequence Data
Neuropeptides
Obesity
Overweight
Pedigree

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1210/jc.2006-1442

Cite this

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title = "Association between neuromedin U gene variants and overweight and obesity",

abstract = "Neuromedin U (NMU) is an anorexic neuropeptide expressed in the hypothalamus. Mice lacking the NmU gene are hyperphagic and obese, whereas mice overexpressing Nmu are hypophagic and lean.",

keywords = "Adolescent, Adult, Aged, Amino Acid Sequence, Body Mass Index, Child, Child, Preschool, Female, Genetic Variation, Humans, Infant, Male, Middle Aged, Molecular Sequence Data, Neuropeptides, Obesity, Overweight, Pedigree",

author = "Irena Hainerov{\'a} and Torekov, {Signe S} and Jakob Ek and Marie Finkov{\'a} and Knut Borch-Johnsen and Torben J{\o}rgensen and Madsen, {Ole D} and Jan Lebl and Torben Hansen and Oluf Pedersen",

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doi = "10.1210/jc.2006-1442",

language = "English",

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pages = "5057--63",

journal = "Journal of Clinical Endocrinology and Metabolism",

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T1 - Association between neuromedin U gene variants and overweight and obesity

AU - Hainerová, Irena

AU - Torekov, Signe S

AU - Ek, Jakob

AU - Finková, Marie

AU - Borch-Johnsen, Knut

AU - Jørgensen, Torben

AU - Madsen, Ole D

AU - Lebl, Jan

AU - Hansen, Torben

AU - Pedersen, Oluf

PY - 2006

Y1 - 2006

N2 - Neuromedin U (NMU) is an anorexic neuropeptide expressed in the hypothalamus. Mice lacking the NmU gene are hyperphagic and obese, whereas mice overexpressing Nmu are hypophagic and lean.

AB - Neuromedin U (NMU) is an anorexic neuropeptide expressed in the hypothalamus. Mice lacking the NmU gene are hyperphagic and obese, whereas mice overexpressing Nmu are hypophagic and lean.

KW - Adolescent

KW - Adult

KW - Aged

KW - Amino Acid Sequence

KW - Body Mass Index

KW - Child

KW - Child, Preschool

KW - Female

KW - Genetic Variation

KW - Humans

KW - Infant

KW - Male

KW - Middle Aged

KW - Molecular Sequence Data

KW - Neuropeptides

KW - Obesity

KW - Overweight

KW - Pedigree

U2 - 10.1210/jc.2006-1442

DO - 10.1210/jc.2006-1442

M3 - Journal article

C2 - 16984985

SN - 0021-972X

VL - 91

SP - 5057

EP - 5063

JO - Journal of Clinical Endocrinology and Metabolism

JF - Journal of Clinical Endocrinology and Metabolism

IS - 12

ER -

Association between neuromedin U gene variants and overweight and obesity

Abstract

Keywords

UN SDGs

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