Abstract
BACKGROUND: Recent studies have shown a higher prevalence of cardiovascular (CV) risk factors in patients with rosacea. However, it remains unknown whether rosacea represents an independent CV risk factor.
OBJECTIVE: We evaluated the risk of myocardial infarction, stroke, CV death, major adverse CV events, and all-cause mortality, respectively.
METHODS: Between January 1, 1997, and December 31, 2012, a total of 4948 patients with rosacea were identified and matched with 23,823 control subjects. We used Poisson regression to calculate incidence rate ratios.
RESULTS: Adjusted incidence rate ratios were 0.75 (95% confidence intervals [CI] 0.57-1.00) for myocardial infarction, 1.08 (95% CI 0.86-1.35) for ischemic stroke, 1.01 (95% CI 0.61-1.67) for hemorrhagic stroke, 0.99 (95% CI 0.80-1.24) for CV death, 0.99 (95% CI 0.86-1.15) for major adverse CV events, and 0.95 (95% CI 0.85-1.06) for all-cause mortality.
LIMITATIONS: We were unable to distinguish between the different subtypes and severities of rosacea.
CONCLUSIONS: In this population-based study, rosacea was not associated with increased risk of adverse CV outcomes or death.
| Original language | English |
|---|---|
| Journal | Journal of the American Academy of Dermatology |
| Volume | 75 |
| Issue number | 2 |
| Pages (from-to) | 336-9 |
| Number of pages | 4 |
| ISSN | 0190-9622 |
| DOIs | |
| Publication status | Published - 1 Aug 2016 |
Keywords
- Cardiovascular Diseases
- Case-Control Studies
- Cause of Death
- Comorbidity
- Female
- Humans
- Incidence
- Male
- Middle Aged
- Poisson Distribution
- Risk Factors
- Rosacea
- Journal Article
