Assessment of left atrial volume and mechanical function in ischemic heart disease: a multi slice computed tomography study

Jørgen Tobias Kühl; Klaus F Kofoed; Jacob E Møller; Sophia Hammer-Hansen; Thomas Kristensen; Lars Køber; Henning Kelbæk; Jørgen Tobias Kühl; Klaus F Kofoed; Jacob E Møller; Sophia Hammer-Hansen; Thomas Kristensen; Lars Køber; Henning Kelbæk

doi:10.1016/j.ijcard.2009.05.029

Assessment of left atrial volume and mechanical function in ischemic heart disease: a multi slice computed tomography study

Jørgen Tobias Kühl, Klaus F Kofoed, Jacob E Møller, Sophia Hammer-Hansen, Thomas Kristensen, Lars Køber, Henning Kelbæk, Jørgen Tobias Kühl, Klaus F Kofoed, Jacob E Møller, Sophia Hammer-Hansen, Thomas Kristensen, Lars Køber, Henning Kelbæk

20 Citations (Scopus)

Abstract

Left atrial (LA) maximal volume contains prognostic information in patients with heart failure and acute myocardial infarction. However, only few studies have investigated the detailed mechanical function of the LA in these patients. We assessed the feasibility of evaluating LA volume and mechanical function with Multi Slice Computed Tomography (MSCT) in patients with ischemic heart disease. Furthermore, the LA and left ventricular (LV) function was evaluated in relation to signs of clinical heart failure. METHODS AND RESULTS: MSCT was performed in 40 patients with sinus rhythm and ischemic heart disease. We enrolled 20 patients with reduced LV ejection fraction (LVEF=45%) and 20 with preserved LVEF (>45%). LA volumes, reservoir, channel and pump function were measured. Interobserver variation for LA volume measures was 1.5% (SD: 6.6%). In patients with reduced LVEF, LA volumes were larger throughout the cardiac cycle (LA-max 66.8 ml/m(2) vs 57.4 ml/m(2) and LA-min: 45.8 ml/m(2) vs 31.6 ml/m(2), p

Original language	English
Journal	International Journal of Cardiology
Volume	145
Issue number	2
Pages (from-to)	197-202
Number of pages	6
ISSN	0167-5273
DOIs	https://doi.org/10.1016/j.ijcard.2009.05.029 https://doi.org/10.1016/j.ijcard.2009.05.029
Publication status	Published - 19 Nov 2010

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Kühl, J. T., Kofoed, K. F., Møller, J. E., Hammer-Hansen, S., Kristensen, T., Køber, L., Kelbæk, H., Kühl, J. T., Kofoed, K. F., Møller, J. E., Hammer-Hansen, S., Kristensen, T., Køber, L., & Kelbæk, H. (2010). Assessment of left atrial volume and mechanical function in ischemic heart disease: a multi slice computed tomography study. International Journal of Cardiology, 145(2), 197-202. https://doi.org/10.1016/j.ijcard.2009.05.029, https://doi.org/10.1016/j.ijcard.2009.05.029

Kühl, JT, Kofoed, KF, Møller, JE, Hammer-Hansen, S, Kristensen, T, Køber, L, Kelbæk, H, Kühl, JT, Kofoed, KF, Møller, JE, Hammer-Hansen, S, Kristensen, T, Køber, L & Kelbæk, H 2010, 'Assessment of left atrial volume and mechanical function in ischemic heart disease: a multi slice computed tomography study', International Journal of Cardiology, vol. 145, no. 2, pp. 197-202. https://doi.org/10.1016/j.ijcard.2009.05.029, https://doi.org/10.1016/j.ijcard.2009.05.029

@article{55cb9ef886ef4db4b87c3edb8f9db3c4,

title = "Assessment of left atrial volume and mechanical function in ischemic heart disease: a multi slice computed tomography study",

abstract = "Left atrial (LA) maximal volume contains prognostic information in patients with heart failure and acute myocardial infarction. However, only few studies have investigated the detailed mechanical function of the LA in these patients. We assessed the feasibility of evaluating LA volume and mechanical function with Multi Slice Computed Tomography (MSCT) in patients with ischemic heart disease. Furthermore, the LA and left ventricular (LV) function was evaluated in relation to signs of clinical heart failure. METHODS AND RESULTS: MSCT was performed in 40 patients with sinus rhythm and ischemic heart disease. We enrolled 20 patients with reduced LV ejection fraction (LVEF=45%) and 20 with preserved LVEF (>45%). LA volumes, reservoir, channel and pump function were measured. Interobserver variation for LA volume measures was 1.5% (SD: 6.6%). In patients with reduced LVEF, LA volumes were larger throughout the cardiac cycle (LA-max 66.8 ml/m(2) vs 57.4 ml/m(2) and LA-min: 45.8 ml/m(2) vs 31.6 ml/m(2), p",

author = "K{\"u}hl, {J{\o}rgen Tobias} and Kofoed, {Klaus F} and M{\o}ller, {Jacob E} and Sophia Hammer-Hansen and Thomas Kristensen and Lars K{\o}ber and Henning Kelb{\ae}k and K{\"u}hl, {J{\o}rgen Tobias} and Kofoed, {Klaus F} and M{\o}ller, {Jacob E} and Sophia Hammer-Hansen and Thomas Kristensen and Lars K{\o}ber and Henning Kelb{\ae}k",

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doi = "10.1016/j.ijcard.2009.05.029",

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T1 - Assessment of left atrial volume and mechanical function in ischemic heart disease: a multi slice computed tomography study

AU - Kühl, Jørgen Tobias

AU - Kofoed, Klaus F

AU - Møller, Jacob E

AU - Hammer-Hansen, Sophia

AU - Kristensen, Thomas

AU - Køber, Lars

AU - Kelbæk, Henning

AU - Kühl, Jørgen Tobias

AU - Kofoed, Klaus F

AU - Møller, Jacob E

AU - Hammer-Hansen, Sophia

AU - Kristensen, Thomas

AU - Køber, Lars

AU - Kelbæk, Henning

PY - 2010/11/19

Y1 - 2010/11/19

N2 - Left atrial (LA) maximal volume contains prognostic information in patients with heart failure and acute myocardial infarction. However, only few studies have investigated the detailed mechanical function of the LA in these patients. We assessed the feasibility of evaluating LA volume and mechanical function with Multi Slice Computed Tomography (MSCT) in patients with ischemic heart disease. Furthermore, the LA and left ventricular (LV) function was evaluated in relation to signs of clinical heart failure. METHODS AND RESULTS: MSCT was performed in 40 patients with sinus rhythm and ischemic heart disease. We enrolled 20 patients with reduced LV ejection fraction (LVEF=45%) and 20 with preserved LVEF (>45%). LA volumes, reservoir, channel and pump function were measured. Interobserver variation for LA volume measures was 1.5% (SD: 6.6%). In patients with reduced LVEF, LA volumes were larger throughout the cardiac cycle (LA-max 66.8 ml/m(2) vs 57.4 ml/m(2) and LA-min: 45.8 ml/m(2) vs 31.6 ml/m(2), p

AB - Left atrial (LA) maximal volume contains prognostic information in patients with heart failure and acute myocardial infarction. However, only few studies have investigated the detailed mechanical function of the LA in these patients. We assessed the feasibility of evaluating LA volume and mechanical function with Multi Slice Computed Tomography (MSCT) in patients with ischemic heart disease. Furthermore, the LA and left ventricular (LV) function was evaluated in relation to signs of clinical heart failure. METHODS AND RESULTS: MSCT was performed in 40 patients with sinus rhythm and ischemic heart disease. We enrolled 20 patients with reduced LV ejection fraction (LVEF=45%) and 20 with preserved LVEF (>45%). LA volumes, reservoir, channel and pump function were measured. Interobserver variation for LA volume measures was 1.5% (SD: 6.6%). In patients with reduced LVEF, LA volumes were larger throughout the cardiac cycle (LA-max 66.8 ml/m(2) vs 57.4 ml/m(2) and LA-min: 45.8 ml/m(2) vs 31.6 ml/m(2), p

U2 - 10.1016/j.ijcard.2009.05.029

DO - 10.1016/j.ijcard.2009.05.029

M3 - Journal article

C2 - 19500864

SN - 0167-5273

VL - 145

SP - 197

EP - 202

JO - International Journal of Cardiology

JF - International Journal of Cardiology

IS - 2

ER -

Assessment of left atrial volume and mechanical function in ischemic heart disease: a multi slice computed tomography study

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